New pill could stop painful swelling attacks for HAE patients
NCT ID NCT02303626
First seen Nov 17, 2025 · Last updated May 07, 2026 · Updated 18 times
Summary
This study tested an oral medication called BCX4161 to prevent sudden swelling attacks in people with hereditary angioedema (HAE), a genetic condition causing painful swelling in the body. About 110 adults with HAE took either a low dose, high dose, or a placebo pill daily for 12 weeks. Researchers tracked how many attacks each person had to see if the drug could reduce their frequency.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Study site
Birmingham, Alabama, 35209, United States
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Study site
Scottsdale, Arizona, 85251, United States
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Granada Hills, California, 91344, United States
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San Diego, California, 92093, United States
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San Diego, California, 92112, United States
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Walnut Creek, California, 94598, United States
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Colorado Springs, Colorado, 80907, United States
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Shreveport, Louisiana, 71106, United States
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Chevy Chase, Maryland, 20815, United States
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Boston, Massachusetts, 02114, United States
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Plymouth, Minnesota, 55446, United States
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St Louis, Missouri, 63141, United States
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New York, New York, 10029, United States
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Charlotte, North Carolina, 28277, United States
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Cincinnati, Ohio, 45267, United States
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Oklahoma City, Oklahoma, 73131, United States
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Tulsa, Oklahoma, 74133, United States
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Lake Oswego, Oregon, 97035, United States
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Hershey, Pennsylvania, 17033, United States
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Pittsburgh, Pennsylvania, 15241, United States
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Dallas, Texas, 75231, United States
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Galveston, Texas, 77555, United States
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Fairfax, Virginia, 63141, United States
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Spokane, Washington, 99204, United States
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Tacoma, Washington, 98405, United States
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Leuven, Belgium
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Ottawa, Canada
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Grenoble, France
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Lille, France
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Paris, France
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Berlin, Germany
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Frankfurt, Germany
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Mörfelden-Walldorf, Germany
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Budapest, Hungary
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Milan, Italy
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Birmingham, United Kingdom
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Bristol, United Kingdom
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Cardiff, United Kingdom
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London, United Kingdom
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Manchester, United Kingdom
Conditions
Explore the condition pages connected to this study.