Brain scans probe opioid's hidden mark on tau protein

NCT ID NCT05651516

First seen Jan 11, 2026 · Last updated May 15, 2026 · Updated 21 times

Summary

This study looks at whether opioid use disorder and non-fatal overdoses cause changes in a brain protein called tau. Researchers will use a special PET scan to measure tau in three groups: people with opioid use disorder who have had an overdose, those with the disorder but no overdose, and healthy volunteers. The goal is to understand brain health, not to test a treatment.

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Contacts and locations

Locations

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.