Should you open that pill? new study tests ulcer healing after bypass surgery

NCT ID NCT05799105

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether opening a capsule of the acid-blocking drug omeprazole helps heal stomach ulcers faster in people who have had gastric bypass surgery. About 122 participants will be randomly assigned to take the capsule whole or opened. Doctors will check ulcer healing with a camera every three months. The goal is to find the simplest, most effective way to treat these ulcers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

omeprazole (Prilosec, Losec)

What this could lead to

If opening the capsule works better, it could give gastric bypass patients a simple way to heal ulcers faster and avoid extra procedures.

What could go wrong

This is a small, early-phase trial with only 122 people. The results may not apply to everyone, and there is no guarantee that opening the capsule will improve healing.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastrojejunal ulcer peptic ulcer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••