Could a cancer drug tame a dangerous heart rhythm?

NCT ID NCT05844501

First seen Feb 04, 2026 · Last updated May 16, 2026 · Updated 12 times

Summary

This study tests whether ondansetron, a drug usually used to prevent nausea in cancer patients, can help people with atrial fibrillation (Afib). Afib is a common irregular heartbeat that can lead to stroke or death. The researchers believe ondansetron may block a specific heart current linked to Afib. They will give 80 people either ondansetron or a placebo for 28 days before their scheduled Afib procedure to see if it reduces Afib episodes and controls heart rate.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Indiana Clinical Research Center

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Indiana University Health Methodist Hospital

    NOT_YET_RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Purdue University

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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