Drug trial aims to halt silent kidney killer

NCT ID NCT03608033

Terminated Disease control Sponsor: Omeros Corporation Source: ClinicalTrials.gov ↗

Summary

This study tested whether the drug OMS721 (narsoplimab) could slow the progression of IgA nephropathy, a kidney disease. It involved about 360 adults with confirmed disease and high levels of protein in their urine. The main goal was to see if the drug could significantly reduce this protein leakage over 36 weeks, which is a key sign of kidney damage.

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Contacts and locations

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Locations

Omeros Investigation Sites

Phoenix, Arizona, 85016, United States
Omeros Investigational Site

Florence, Alabama, 35630, United States
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Mesa, Arizona, 85206, United States
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Scottsdale, Arizona, 85258, United States
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Scottsdale, Arizona, 85259, United States
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Los Angeles, California, 90022-4302, United States
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Los Angeles, California, 90025, United States
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Northridge, California, 91324, United States
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San Dimas, California, 91773, United States
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San Francisco, California, 94118, United States
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Stanford, California, 94304, United States
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Torrance, California, 90509, United States
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Denver, Colorado, 80230, United States
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Miami, Florida, 33136, United States
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Miami Lakes, Florida, 33014, United States
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Lawrenceville, Georgia, 30046, United States
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Chicago, Illinois, 60612, United States
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Iowa City, Iowa, 52242, United States
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Boston, Massachusetts, 02111, United States
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Springfield, Massachusetts, 01107, United States
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Minneapolis, Minnesota, 55414, United States
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Rochester, Minnesota, 55905, United States
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St Louis, Missouri, 63110, United States
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Fresh Meadows, New York, 11365, United States
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New York, New York, 10029, United States
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Cincinnati, Ohio, 45220, United States
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Columbus, Ohio, 43210, United States
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Philadelphia, Pennsylvania, 19104, United States
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Charleston, South Carolina, 29425, United States
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Chattanooga, Tennessee, 37404, United States
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Amarillo, Texas, 79106, United States
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Dallas, Texas, 75246, United States
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Houston, Texas, 77054, United States
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Milwaukee, Wisconsin, 53226, United States
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Posadas, Misiones Province, 3300, Argentina
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Buenos Aires, C1280AEB, Argentina
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Córdoba, X5016KEH, Argentina
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Salta, 4400, Argentina
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Garran, Australian Capital Territory, Woden, 2606, Australia
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Footscray, Saint Albans, 3021, Australia
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Adelaide, South Australia, 5000, Australia
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Clayton, Victoria, 3168, Australia
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Ghent, 9000, Belgium
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Leuven, 3000, Belgium
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Liège, 1-4000, Belgium
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Plovdiv, 4000, Bulgaria
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Plovdiv, 4002, Bulgaria
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Sofia, 1431, Bulgaria
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Vancouver, British Columbia, V5Z2M9, Canada
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Vancouver, British Columbia, V6Z1Y6, Canada
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London, Ontario, N6A545, Canada
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Toronto, Ontario, M5G2C4, Canada
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Prague, Prague, 128 08, Czechia
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Mannheim, Baden-Wrttemberg, 68167, Germany
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München, Bavaria, 80336, Germany
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Aachen, North Rhine-Westphalia, 52074, Germany
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Göttingen, 37075, Germany
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Villingen-Schwenningen, 78052, Germany
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Thessaloniki, Pilea-Chortiatis, 57010, Greece
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Athens, 11527, Greece
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Heraklion, 71110, Greece
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Heraklion, 71409, Greece
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Pátrai, 26504, Greece
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Baja, H-6500, Hungary
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Budapest, H-1097, Hungary
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Győr, H-9024, Hungary
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Pécs, H-7624, Hungary
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Szeged, 6720, Hungary
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Hyderabad, Ameerpet, 500038, India
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Nadiād, Gujarat, 387001, India
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Belagavi, Karnataka, 590010, India
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Mangalore, Karnataka, 575001, India
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Kozhikode, Kerala, 673008, India
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New Delhi, New India, 110017, India
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Jaipur, Rajasthan, 302004, India
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Hyderabad, Telangana, 500034, India
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Hyderabad, Telangana, 500038, India
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Hyderabad, Telangana, 500082, India
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Chandigarh, 160012, India
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Bari, 70124, Italy
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Bergamo, 24127, Italy
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Eboli, 84025, Italy
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Messina, 98125, Italy
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Milan, 20122, Italy
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Modena, 41124, Italy
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Parma, 43126, Italy
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Piacenza, 29121, Italy
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Kaunas, LT-50161, Lithuania
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Vilnius, LT-08661, Lithuania
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Lodz, Todzi, 92-213, Poland
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Krakow, 30-688, Poland
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Olsztyn, 10-561, Poland
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Warsaw, 04-749, Poland
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Singapore, 119074, Singapore
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Singapore, 308433, Singapore
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Banská Bystrica, 97401, Slovakia
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Košice, 04011, Slovakia
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Seongnam, Geyonggi-do, 13496, South Korea
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Anyang-si, Gyeonggi-do, 14068, South Korea
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Busan, 49241, South Korea
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Incheon, 21431, South Korea
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Seoul, 05278, South Korea
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Seoul, 07061, South Korea
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Seoul, 3080, South Korea
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Seoul, 3722, South Korea
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Madrid, San Sebastian de Lost Reyes, 28702, Spain
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Almería, 04009, Spain
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Barcelona, 08025, Spain
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Córdoba, 14004, Spain
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Lleida, 25198, Spain
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Madrid, 28040, Spain
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Madrid, 28041, Spain
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Valencia, 46026, Spain
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Zaragoza, 50009, Spain
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Stockholm, Sweden
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Changhua, 500, Taiwan
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Hualien City, 97002, Taiwan
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Kaohsiung City, 824, Taiwan
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New Taipei City, 220, Taiwan
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New Taipei City, 235, Taiwan
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Taichung, Taiwan
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Taoyuan, 333, Taiwan
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Bangkok, 10300, Thailand
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Bangkok, 10700, Thailand
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Chiang Mai, 50200, Thailand
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Dusit, Thailand
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Khon Kaen, 40000, Thailand
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Songkhla, 90000, Thailand
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Ankara, 06230, Turkey (Türkiye)
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Bursa, 16059, Turkey (Türkiye)
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Edirne, 22130, Turkey (Türkiye)
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Istanbul, 34899, Turkey (Türkiye)
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Kocaeli, 41380, Turkey (Türkiye)
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Malatya, 44200, Turkey (Türkiye)
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Leicester, Evington, LE5 4PW, United Kingdom
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Cambridge, CB2 0QQ, United Kingdom
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Cardiff, CF10 3XQ, United Kingdom
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Dartford, DA2 8DA, United Kingdom
Omeros Investigational Site

London, NW3 2QG, United Kingdom

Conditions

Explore the condition pages connected to this study.

IGA NEPHROPATHY