Fish oil cocktail takes on stubborn ear fluid in adults
NCT ID NCT07721610
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This trial tests whether a daily supplement containing omega-3s, Spirulina, magnesium, and vitamin B6 can help adults with persistent middle ear fluid — a condition that can cause hearing loss and ear fullness. Over 500 adults aged 18 to 70 with confirmed otitis media with effusion will receive the supplement, an antihistamine, or a placebo, all on top of standard anti-inflammatory treatment. The goal is to see if the supplement improves ear pressure and hearing more than the other options.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a nutraceutical combination of omega-3 fatty acids, Spirulina, magnesium, and vitamin B6
- What this could lead to
- If effective, this supplement could offer a well-tolerated option to help clear middle ear fluid and improve hearing in adults, reducing the need for more invasive treatments.
- What could go wrong
- This is a Phase 4 trial, but the supplement is tested as an add-on to standard therapy, so its standalone benefit is unclear. Results may not apply to all patients, and side effects from the supplement are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Isola Tiberina - Gemelli Isola Hospital Rome, Italy
Roma, Italy, 00100, Italy