New combo therapy targets hard-to-treat blood cancers in phase 2 trial

NCT ID NCT07153497

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 31 times

Summary

This study tests whether adding the drug olutasidenib to standard treatments helps people with certain blood cancers (AML or MDS) that have an IDH1 gene mutation. About 132 adults will receive either standard therapy alone or with olutasidenib. The goal is to see if the combination leads to higher remission rates and better blood counts.

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