New hope for rare brain fungus: experimental drug olorofim tested
NCT ID NCT07385638
First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 2 times
Summary
This study tests a drug called olorofim in people recently diagnosed with coccidioidal meningitis, a rare fungal infection of the brain and spinal cord. About 12 participants will take olorofim and be followed for 6 months to see if it is safe and helps control the infection. The goal is to gather early information on whether this drug could be a future treatment option.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- olorofim
- What this could lead to
- If it works, this could point toward a new treatment option for a rare and serious fungal brain infection.
- What could go wrong
- This is a very small, early-phase study with only 12 people, so results may not apply broadly. The drug may not work or could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for COCCIDIOIDAL MENINGITIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Banner University Medical Center
RECRUITINGTucson, Arizona, 85719, United States