New hope for hard-to-treat breast cancer? drug targets hidden genetic switch

NCT ID NCT05522491

First seen Jan 03, 2026 · Last updated Apr 30, 2026 · Updated 15 times

Summary

This study tests the drug olaparib in 30 women with advanced triple-negative breast cancer that has come back or spread. Unlike other studies, it focuses on patients whose tumors have a specific chemical change (methylation) in the BRCA1 gene, but no BRCA1/2 mutations. The goal is to see if the drug can shrink tumors or slow the cancer's growth.

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Conditions

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