Experimental combo targets tough lymphomas in early trial

NCT ID NCT03259503

First seen Sep 30, 2025 · Last updated May 30, 2026 · Updated 38 times

Summary

This early-phase study tested the safety and best dose of the drug olaparib when combined with high-dose chemotherapy for people with lymphomas that returned or didn't respond to treatment. The 50 participants received this combination before a stem cell transplant. The goal was to see if adding olaparib could make the chemotherapy more effective without causing too many side effects.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.