New drug combo shows promise for tough lymphomas

NCT ID NCT03259503

First seen Sep 30, 2025 · Last updated May 06, 2026 · Updated 35 times

Summary

This early-phase trial tested the safety and best dose of olaparib combined with high-dose chemotherapy in 50 adults with lymphomas that returned or didn't respond to treatment. Participants received the drug combo before a stem cell transplant. The goal was to see if adding olaparib could help kill cancer cells more effectively, but lifelong monitoring and potential ongoing treatment are still needed.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.