New shot tested to fight blurred vision and droopy eyelids

NCT ID NCT06558279

Ongoing Disease control Sponsor: argenx Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a medication called efgartigimod, given as an injection, can help adults with ocular myasthenia gravis. Ocular myasthenia gravis causes weakness in the eye muscles, leading to problems like double vision and drooping eyelids. For the first 7 weeks, half the participants will receive the real medication and half will receive a placebo (inactive shot), then all participants can receive the real medication for up to 2 years to see if it safely reduces symptoms and improves daily life.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AORN Antonio Cardarelli

Naples, 80131, Italy
ASST Papa Giovanni XXIII - Ospedale Papa Giovanni XXIII

Bergamo, 24127, Italy
Aarhus Universitetshospital

Aarhus N, 8200, Denmark
Azienda Ospedaliero-Universitaria Sant'Andrea

Roma, 00189, Italy
Box Hill Hospital

Box Hill, 3128, Australia
CLINIREM Sp z o.o.

Lublin, 20-064, Poland
Centre Hospitalier de l'Universite de Montreal

Montreal, H2X 0A9, Canada
Centrum Medyczne Neurologia Slaska

Katowice, 40-689, Poland
Charité - Universitätsmedizin Berlin

Berlin, 13353, Germany
Chiba University Hospital

Chūōku, 260-8677, Japan
Cleveland Clinic

Cleveland, Ohio, 44195, United States
Cyprus Institute of Neurology and Genetics

Égkomi, 2371, Cyprus
Dementech Neurosciences Clinical Academic Centre

London, W1G 9ST, United Kingdom
Duke Neurological Disorders Clinic

Durham, North Carolina, 27710, United States
Eginitio Hospital

Athens, 115 28, Greece
Fakultni nemocnice Brno

Brno, 625 00, Czechia
Fondazione IRCCS Istituto Neurologico Carlo Besta

Milan, 20133, Italy
Fujian Medical University Union Hospital

Fuzhou, 350001, China
General Hanamaki Hospital

Hanamaki-shi, 025-0075, Japan
Gold Coast University Hospital

Southport, 4215, Australia
Guangdong Province Traditional Chinese Medical Hospital

Guangzhou, 510120, China
Henry Ford Health System

Detroit, Michigan, 48202, United States
Hiroshima University Hospital

Hiroshima, 734-8551, Japan
HonorHealth Neurology - Bob Bové Neuroscience Institute

Scottsdale, Arizona, 85251, United States
Hopital de L'enfant Jesus

Québec, G1J 1Z4, Canada
Hospital Clinico San Carlos

Madrid, 28040, Spain
Hospital Clinico Universitario de Valencia

Valencia, 46010, Spain
Hospital Universitario Ramon y Cajal

Madrid, 28304, Spain
Hospital Universitario Vall d'Hebron

Barcelona, 08035, Spain
Hospital Universitario de Donostia

San Sebastián, 20014, Spain
Hospital del Mar

Barcelona, 8003, Spain
Houston Methodist Neurological Institute

Houston, Texas, 77030, United States
Huashan Hospital Fudan University

Shanghai, 200040, China
Hôpital Fondation Adolphe de Rothschild

Paris, 75019, France
Hôpital de la Citadelle

Liège, 4000, Belgium
IRCCS Istituto dell Scienze Neurologiche di Bologna

Bologna, 40139, Italy
IUHW Narita Hospital

Narita, 286-8520, Japan
Kindai University Hospital

Sayama, 589-8511, Japan
Korea University Anam Hospital

Seoul, 2841, South Korea
Krakowska Akademia Neurologii

Krakow, 31-505, Poland
Kyungpook National University Chilgok hospital

Daegu, 41404, South Korea
Kyushu University Hospital

Fukuoka, 812-8582, Japan
LLC Caucasus Medical Centre

Tbilisi, 186, Georgia
Leeds General Infirmary

Leeds, LS1 3EX, United Kingdom
Leids Universitair Medisch Centrum

Leiden, 2333 ZA, Netherlands
Loma Linda University Health

Loma Linda, California, 92354, United States
London Health Sciences Centre

London, N6A 5A5, Canada
MICS Centrum Medyczne Bydgoszcz

Bydgoszcz, 85-065, Poland
Maritime Neurology

Halifax, B3R 1V9, Canada
Martha Morehouse Medical plaza

Columbus, Ohio, 43221, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Mediclinic Parkview

Dubai, 51122, United Arab Emirates
National Hospital Organization Hokkaido Medical Center

Sapporo, 063-0005, Japan
National Hospital Organization Utano National Hospital

Kyoto, 616-8255, Japan
National Neuromuscular Research Institute

Austin, Texas, 78759-8402, United States
Nemocnice Pardubickeho kraje, a.s., Pardubicka nemocnice

Pardubice, 532 03, Czechia
Neurology Associates PA

Maitland, Florida, 32751, United States
Neurology Offices of South Florida

Boca Raton, Florida, 33428-4221, United States
New Hospitals

Tbilisi, 114, Georgia
Northwestern Memorial Hospital

Chicago, Illinois, 60611, United States
Osaka University Hospital

Suita-Shi, 565-0871, Japan
Ospedale San Raffaele S.r.l.

Milan, 20132, Italy
Ottawa Hospital Research Institute

Ottawa, K1Y 4E9, Canada
Panthera Biopartners - Glasgow

Glasgow, G51 4TY, United Kingdom
Penn Medicine University City

Philadelphia, Pennsylvania, 19104, United States
Petre Sarajishvili Institute of Neurology

Tbilisi, 112, Georgia
Pineo Medical Ecosystem

Tbilisi, 114, Georgia
Qilu Hospital of Shandong University

Jinan, 250012, China
Renmin Hospital of Wuhan University - Main Campus

Wuhan, 430060, China
Rigshospitalet

Copenhagen, 2100, Denmark
Robert Wood Johnson Medical School

New Brunswick, New Jersey, 08901, United States
Royal Sussex County Hospital

Brighton, BN2 5BE, United Kingdom
SFM Clinical Research, LLC

Boca Raton, Florida, 33487-2768, United States
SP ZOZ Szpital Uniwersytecki

Krakow, 31-503, Poland
Sahlgrenska Universitetssjukhuset

Gothenburg, 413 45, Sweden
Saitama Medical Center

Kawagoe, 350-0844, Japan
Severance Hospital Yonsei University Health System

Seoul, 3722, South Korea
Shijiazhuang People's Hospital - Fangbeilu Campus

Shijiazhuang, 050011, China
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital

Chengdu, 610072, China
Southampton General Hospital

Southampton, SO16 6YD, United Kingdom
The Alfred Hospital

Melbourne, 3004, Australia
The First Affiliated Hospital of Chongqing Medical University

Chongqing, 400016, China
The First Affiliated Hospital of Guangzhou University Chinese Medicine

Guangzhou, 510405, China
The First Affiliated Hospital of Nanchang University - Xianghu Campus

Nanchang, 330000, China
Tokyo Medical University Hospital

Shinjuku-Ku, 160-0023, Japan
Tongji Hospital Tongji Medical College Huazhong University of Science and Technology

Wuhan, 430030, China
Toronto General Hospital

Toronto, M5G 2C4, Canada
Turun Yliopistollinen Keskussairaala

Turku, 20521, Finland
ULS de Santa Maria, EPE - Hospital de Santa Maria

Lisbon, 1649-035, Portugal
ULS de Santo António, EPE - Hospital de Santo António

Porto, 4099-001, Portugal
USC Roski Eye Institute - Los Angeles

Los Angeles, California, 90033, United States
UZ Leuven

Leuven, 3000, Belgium
University Clinical Center Nis

Niš, 18 000, Serbia
University Clinical Center of Serbia

Belgrade, 11000, Serbia
University General Hospital of Patras

Pátrai, 265 04, Greece
University of California Irvine

Columbia, Maryland, 21044, United States
University of California San Francisco

San Francisco, California, 94143, United States
University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27514, United States
University of South Florida

Tampa, Florida, 33620, United States
Universität Georg August

Göttingen, 37075, Germany
Universitätsklinikum AKH Wien

Vienna, 1090, Austria
Xiangya Hospital Central South University

Changsha, 410008, China

Conditions

Explore the condition pages connected to this study.

MYASTHENIA GRAVIS, OCULAR