One-Shot gene therapy tested to halt blinding eye disease

NCT ID NCT06018558

Summary

This early-stage study is testing a one-time gene therapy injection called OCU410 for people with geographic atrophy, an advanced form of dry age-related macular degeneration that causes progressive vision loss. The trial aims to see if the treatment is safe and if it can slow the growth of the eye damage. Up to 60 participants will receive either the experimental injection or no treatment to compare results.

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Contacts and locations

Locations

  • A) Retina Foundation of the Southwest

    Dallas, Texas, 75231, United States

  • Advanced Research, LLC

    Coral Springs, Florida, 33067, United States

  • Associated Retina Consultants

    Phoenix, Arizona, 85020, United States

  • B) Retina Consultants of Texas

    Bellaire, Texas, 77401, United States

  • Duke Eye Center

    Durham, North Carolina, 27710, United States

  • Gundersen Health System

    La Crosse, Wisconsin, 54601, United States

  • Mid Atlantic Retina

    Cherry Hill, New Jersey, 08034, United States

  • Miidwest Eye Institute

    Carmel, Indiana, 46290, United States

  • Mississippi Retina Associates

    Jackson, Mississippi, 39202, United States

  • The Retina Institute

    St Louis, Missouri, 63128, United States

  • The University of Pittsburgh

    Pittsburgh, Pennsylvania, 15260, United States

  • Valley retina Institute

    McAllen, Texas, 78503, United States

Conditions

Explore the condition pages connected to this study.