New drug trial offers hope for kids with severe lupus kidney damage

NCT ID NCT05039619

Recruiting now Disease control Sponsor: Hoffmann-La Roche Source: ClinicalTrials.gov ↗

Summary

This study is testing an investigational drug called obinutuzumab in children and adolescents with a severe form of lupus that attacks the kidneys, known as lupus nephritis. The goal is to see if the drug can help control the kidney disease and allow patients to reduce their use of steroid medications. About 40 participants, aged 5 to 18, will receive either the study drug or a placebo to compare safety and effectiveness over 76 weeks.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Alder Hey Childrens Hospital
RECRUITING

Liverpool, L12 2AP, United Kingdom
CH de Bicêtre
RECRUITING

Le Kremlin-Bicêtre, 94275, France
CHU de Toulouse - Hôpital des Enfants
RECRUITING

Toulouse, 31000, France
CREA Hospital Mexico Americano
RECRUITING

Guadalajara, Jalisco, 44620, Mexico
Centro de Pesquisa São Lucas
RECRUITING

Campinas, São Paulo, 13060-904, Brazil
Children's Hospital Colorado, Anchutz Medical Campus
RECRUITING

Aurora, Colorado, 80045, United States
Chldren?s Hospital of Philadelphia
WITHDRAWN

Philadelphia, Pennsylvania, 19104, United States
Cincinnati Childrens Hospital
RECRUITING

Cincinnati, Ohio, 45229, United States
Clinica El Golf
ACTIVE_NOT_RECRUITING

San Isidro, L27 Lima, Peru
Clinica Pediatrica II De Marchi
RECRUITING

Milan, Lombardy, 20122, Italy
Clinstile S.A de C.V.
RECRUITING

Mexico City, Mexico CITY (federal District), 06700, Mexico
Cohen Children's Medical Center of New York
RECRUITING

Queens, New York, 11042, United States
Emory Children's Center
RECRUITING

Atlanta, Georgia, 30322, United States
Great Ormond Street Hospital for Children
RECRUITING

London, WC1N 3JH, United Kingdom
Groote Schuur Hospital
WITHDRAWN

Cape Town, 7925, South Africa
Hackensack University Medical Center
RECRUITING

Hackensack, New Jersey, 07601, United States
Hop Necker Enfants Malades
RECRUITING

Paris, 75743, France
Hospital Ramon y Cajal
RECRUITING

Madrid, 28034, Spain
Hospital Sainte-Justine
RECRUITING

Montreal, Quebec, H3T 1C5, Canada
Hospital Sant Joan De Deu
RECRUITING

Esplugas de Llobregat, Barcelona, 08950, Spain
Hospital Universitario Dr. Jose Eleuterio Gonzalez
RECRUITING

Monterrey, Nuevo León, 64460, Mexico
Hospital Universitario la Fe: Servicio de Reumatologia Pediatrica
RECRUITING

Valencia, 46026, Spain
Hospital das Clinicas - FMUSP
RECRUITING

São Paulo, São Paulo, 05403-000, Brazil
Hospital de La Paz
RECRUITING

Madrid, 28046, Spain
Hôpital Robert Debré
RECRUITING

Paris, 75019, France
IRCCS G. Gaslini
RECRUITING

Genoa, Liguria, 16148, Italy
Indiana University Health University Hospital
RECRUITING

Indianapolis, Indiana, 46202, United States
Instituto de Ginecología y Reproducción
ACTIVE_NOT_RECRUITING

Lima, Peru
Loma Linda University health
RECRUITING

Loma Linda, California, 92354, United States
Louisiana State University
RECRUITING

Shreveport, Louisiana, 71103, United States
Ospedale Pediatrico Bambino Gesu
RECRUITING

Rome, Lazio, 00165, Italy
Panaroma Medical Center
RECRUITING

Panorama, 7500, South Africa
Red Cross War Memorial Children?s Hospital
WITHDRAWN

Cape Town, 7700, South Africa
Royal Hospital For Children
WITHDRAWN

Glasgow, G51 4TF, United Kingdom
Saint-Petersburg State
WITHDRAWN

St-peterburg, Sankt-Peterburg, 194100, Russia
Ser Servicos Especializados Em Reumatologia
RECRUITING

Salvador, Estado de Bahia, 40150-150, Brazil
Szpital Specjalistyczny dla Dzieci i Doroslych
WITHDRAWN

Torun, 87-100, Poland
Texas Arthritis Center
WITHDRAWN

El Paso, Texas, 79902, United States
The Hospital for Sick Children
RECRUITING

Toronto, Ontario, M5G 1X8, Canada
UCSF Benioff Childrens Hospital
RECRUITING

San Francisco, California, 94158, United States
Universidade Federal de Sao Paulo - UNIFES
ACTIVE_NOT_RECRUITING

São Paulo, 04024-002, Brazil
Uniwersyteckie Centrum Kliniczne
RECRUITING

Gdansk, 80-294, Poland

Conditions

Explore the condition pages connected to this study.

LUPUS NEPHRITIS