New Dual-Target CAR t therapy takes on Hard-to-Treat myeloma

NCT ID NCT07369895

First seen Jan 31, 2026 · Last updated May 14, 2026 · Updated 19 times

Summary

This early-phase study tests a new treatment called O&D-001 for people with multiple myeloma that has returned or stopped responding to standard therapies. The treatment uses specially engineered immune cells (CAR T cells) that target two proteins on myeloma cells: BCMA and GPRC5D. The main goals are to check safety and find the right dose in 18 adults aged 18 to 75.

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Contacts and locations

Locations

  • Sun Yat-sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.