New hope for myelofibrosis patients as novel pill enters trials

NCT ID NCT04176198

Recruiting now Disease control Sponsor: Sumitomo Pharma America, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing a new oral medication called nuvisertib for people with intermediate or high-risk myelofibrosis, a serious bone marrow cancer. It aims to find a safe dose and see if the drug can reduce spleen size and ease symptoms. The trial is enrolling about 240 patients, including those who have not responded well to or cannot take standard treatments.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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ASST - Spedali Civili di Brescia
RECRUITING

Brescia, Italy

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Aichi Medical University Hospital
RECRUITING

Aichi, Japan

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Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo
RECRUITING

Alessandria, 15121, Italy

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Azienda Ospedaliera Universitaria Citta' Della Salute E della Scienza di Torino
RECRUITING

Torino, 10126, Italy

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Baptist Health - Miami Cancer Institute
RECRUITING

Miami, Florida, 33176, United States

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Blood Cancer Center
RECRUITING

Denver, Colorado, 80218, United States

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CHU Angers
RECRUITING

Angers, 9000, France

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CHU de Liege
RECRUITING

Liège, 4000, Belgium

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Centre Hospitalier Lyon Sud
RECRUITING

Lyon, 69495, France

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Centre Hospitalier Universitaire D'Amiens
RECRUITING

Amiens, 80054, France

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City of Hope
RECRUITING

Duarte, California, 91010, United States

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Duke Cancer Institute
RECRUITING

Durham, North Carolina, 27710, United States

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Eastern Health Box Hill Hospital
RECRUITING

Box Hill, Victoria, Australia

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Emory University
RECRUITING

Atlanta, Georgia, 30322, United States

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Epworth Healthcare
RECRUITING

Richmond, Victoria, Australia

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Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
RECRUITING

Milan, 20122, Italy

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Hoag Family Cancer Institute
RECRUITING

Newport Beach, California, 92663, United States

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Hokkaido University Hospital
RECRUITING

Hokkaido, Japan

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Hospital Saint Louis
RECRUITING

Paris, 75010, France

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Hospitalier Universitaire (CHU) de Nice - Hopital de l'Archet
RECRUITING

Nice, 06200, France

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Huntsman Cancer Institute
RECRUITING

Salt Lake City, Utah, 84112, United States

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IRCCS Azienda Ospedaliero -Universitaria Di Bologna - Dipartimento Malattie Oncologiche ed Ematologiche - UO Ematologia
RECRUITING

Bologna, 40138, Italy

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IRCCS istituto Romagnolo per lo studio dei tumori "Dino Amadori"
RECRUITING

Meldola, 47014, Italy

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Icahn School of Medicine at Mount Sinai
RECRUITING

New York, New York, 10029, United States

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Icon Cancer Centre (Ashford Cancer Centre Research)
RECRUITING

Adelaide, Australia

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Institut Gustave Roussy
RECRUITING

Villejuif, 94805, France

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Institut de cancerologie du Gard
RECRUITING

Nîmes, 30029, France

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Institut de cancerologie du Gard
RECRUITING

Nîmes, France

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Istituto Nazionale Tumori, IRCCS Centro di Riferimento Oncologico di Aviano
RECRUITING

Aviano, 33081, Italy
Jewish General Hospital
RECRUITING

Montreal, Quebec, H3T 1E2, Canada

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John Theurer Cancer Center at Hackensack University Medical Center
RECRUITING

Hackensack, New Jersey, 07601, United States

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Juntendo University Hospital
RECRUITING

Tokyo, Japan

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Juravinski Cancer Center
NOT_YET_RECRUITING

Hamilton, Ontario, L8V 5C2, Canada

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Kyushu University Hospital
RECRUITING

Fukuoka, Japan

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Lincoln County Hospital
RECRUITING

Lincoln, United Kingdom

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MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77054, United States

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Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States

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Medical University of South Carolina
NOT_YET_RECRUITING

Charleston, South Carolina, 29425, United States

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Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States

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Mie University Hospital
RECRUITING

Tsu, Japan

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Monash University
RECRUITING

Clayton, Victoria, Australia

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Montefiore Cancer Center
RECRUITING

The Bronx, New York, 10461, United States

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National Cancer Center Hospital East
RECRUITING

Chiba, Japan

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Ohio State University
RECRUITING

Columbus, Ohio, 43210, United States

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Okayama University Hospital
RECRUITING

Okayama, Japan

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Oxford University Hospitals NHS Foundation
RECRUITING

Oxford, United Kingdom

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Peter McCallum Center
RECRUITING

Melbourne, Victoria, Australia

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Princess Margaret Cancer Center
RECRUITING

Toronto, Ontario, M5G 2M9, Canada

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Roswell Park Comprehensive Cancer Center
COMPLETED

Buffalo, New York, 14263, United States
Royal Adelaide Hospital
RECRUITING

Adelaide, South Australia, Australia

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Saitama Medical Center
RECRUITING

Saitama, Japan

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Shizuoka Cancer Center
COMPLETED

Shizuoka, Japan
Shonan Kamakura General Hospital
RECRUITING

Kamakura, 247-8533, Japan

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St. Paul's Hospital Hematology/Oncology Research
RECRUITING

Vancouver, British Columbia, V6T 1Z3, Canada

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The University of Arizona Cancer Center
RECRUITING

Tucson, Arizona, 85724, United States

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The University of Osaka Hospital
RECRUITING

Osaka, Japan

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Tohoku University Hospital
RECRUITING

Sendai, Japan

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Tokyo Medical University Hospital
RECRUITING

Tokyo, 160-0023, Japan

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Tri-Star Centennial Medical Center
RECRUITING

Nashville, Tennessee, 37203, United States

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United Lincolnshire Hospitals NHS Trust - Pilgrim Hospital
RECRUITING

Lincoln, United Kingdom

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Universitair Ziekenhuis Gent
RECRUITING

Ghent, 9000, Belgium

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University College London Hospital's NHS foundation Trust
RECRUITING

London, United Kingdom

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University Hospital of Poitiers
RECRUITING

Poitiers, 86021, France

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University Hospitals Leuven
RECRUITING

Leuven, Vlaams-Brabant, 3000, Belgium

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University of Alabama
RECRUITING

Birmingham, Alabama, 35294, United States

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University of British Columbia
RECRUITING

Vancouver, British Columbia, V6T 1Z3, Canada

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University of Calgary
RECRUITING

Calgary, Alberta, T2N 1N4, Canada

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University of Chicago
RECRUITING

Chicago, Illinois, 60637, United States

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University of Florida Health Shands Cancer Hospital
COMPLETED

Gainesville, Florida, 32608, United States
University of Maryland
RECRUITING

Baltimore, Maryland, 21201, United States

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University of Miami
RECRUITING

Miami, Florida, 33136, United States

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University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States

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University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States

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University of Miyazaki Hospital
RECRUITING

Miyazaki, Japan

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University of Southern California
RECRUITING

Los Angeles, California, 90033, United States

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University of Virginia Cancer Center
RECRUITING

Charlottesville, Virginia, 22903, United States

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University of Washington - Fred Hutchinson Cancer Center
RECRUITING

Seattle, Washington, 98109, United States

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Vanderbilt University
RECRUITING

Nashville, Tennessee, 37232, United States

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Washington University of Medicine
RECRUITING

St Louis, Missouri, 63110, United States

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Weill Cornell Medical Center
RECRUITING

New York, New York, 10065, United States

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Yale School of Medicine
RECRUITING

New Haven, Connecticut, 06510, United States

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ZNA Cadix
RECRUITING

Antwerp, 2020, Belgium

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ZNA Middelheim
RECRUITING

Antwerp, 2030, Belgium

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Conditions

Explore the condition pages connected to this study.

MYELOFIBROSIS