Could a brain chemical blocker ease social anxiety? new trial launches

NCT ID NCT07323784

Recruiting now Symptom relief Sponsor: Newleos Therapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 2 times

Summary

This Phase 2 trial tests whether a new drug called NTX-1472 can safely reduce symptoms of social anxiety disorder. About 100 adults will take either the drug or a placebo daily for 8 weeks. Researchers will measure changes in anxiety and avoidance using a standard scale, and track any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: NTX-1472 (a V1a receptor antagonist)
What this could lead to: If it works, this could point toward a new treatment option for social anxiety disorder that works differently from current medications.
What could go wrong: This is an early Phase 2 trial with only 100 participants, so results may not apply to everyone. The drug may not prove more effective than placebo, and side effects are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

social phobia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOCIAL ANXIETY DISORDER (SAD)

Contacts and locations

Locations

SOAR Clinical Study Site
RECRUITING

Encino, California, 91316, United States
SOAR Clinical Study Site
RECRUITING

Los Angeles, California, 90025, United States
SOAR Clinical Study Site
RECRUITING

Oceanside, California, 92056, United States
SOAR Clinical Study Site
RECRUITING

San Jose, California, 95124, United States
SOAR Clinical Study Site
RECRUITING

Jacksonville, Florida, 32256, United States
SOAR Clinical Study Site
RECRUITING

Tampa, Florida, 33615, United States
SOAR Clinical Study Site
RECRUITING

Boston, Massachusetts, 02131, United States
SOAR Clinical Study Site
ACTIVE_NOT_RECRUITING

Las Vegas, Nevada, 89119, United States
SOAR Clinical Study Site
RECRUITING

Brooklyn, New York, 11229, United States
SOAR Clinical Study Site
RECRUITING

Memphis, Tennessee, 38119, United States
SOAR Clinical Study Site
RECRUITING

Austin, Texas, 78737, United States

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