Gene-Editing breakthrough tested for rare, fatal heart and nerve disease

NCT ID NCT04601051

Summary

This early-stage study tested a new, one-time gene-editing treatment called NTLA-2001 for people with hereditary forms of amyloidosis, a disease where a harmful protein builds up and damages the heart or nerves. The main goal was to check the safety of the treatment and see how it behaves in the body. Researchers also looked for early signs that the treatment could reduce the harmful protein and potentially slow the disease.

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Contacts and locations

Locations

  • Clinical Trial Site

    Paris, France

  • Clinical Trial Site

    Auckland, New Zealand

  • Clinical Trial Site

    Umeå, Sweden

  • Clinical Trial Site

    London, United Kingdom

Conditions

Explore the condition pages connected to this study.