New shot aims to tame painful swallowing disorder

NCT ID NCT06598462

Ongoing Disease control Sponsor: Uniquity One (UNI) Source: ClinicalTrials.gov ↗

Summary

This study is testing an investigational drug called NSI-8226 (solrikitug) to see if it can help adults with eosinophilic esophagitis (EoE), a condition that causes painful swallowing and inflammation in the food pipe. About 184 participants will receive either the drug or a placebo as a shot under the skin for 24 weeks, with an option to continue for another 28 weeks. The main goals are to see if the drug reduces inflammation in the esophagus and improves swallowing symptoms compared to a placebo.

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Contacts and locations

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Locations

Research Site 1001

Jacksonville, Florida, 32256, United States
Research Site 1002

Ogden, Utah, 84405, United States
Research Site 1003

Tucson, Arizona, 85715, United States
Research Site 1004

Boston, Massachusetts, 02111, United States
Research Site 1005

Irvine, California, 92618, United States
Research Site 1006

Plymouth, Minnesota, 55446, United States
Research Site 1007

Boise, Idaho, 83706, United States
Research Site 1008

Houston, Texas, 77494, United States
Research Site 1012

Columbus, Ohio, 43213, United States
Research Site 1013

Wyoming, Michigan, 49519, United States
Research Site 1014

Dallas, Texas, 75230, United States
Research Site 1015

San Diego, California, 92120, United States
Research Site 1016

Reno, Nevada, 89511, United States
Research Site 1017

Sandy City, Utah, 84092, United States
Research Site 1018

Glendale, Arizona, 85306, United States
Research Site 1018

Peoria, Arizona, 85306, United States
Research Site 1019

Salt Lake City, Utah, 84132, United States
Research Site 1020

Harrisburg, Pennsylvania, 17110, United States
Research Site 1021

High Point, North Carolina, 27265, United States
Research Site 1022

Iowa City, Iowa, 52242, United States
Research Site 1023

Englewood, California, 90301, United States
Research Site 1024

Ann Arbor, Michigan, 48109, United States
Research Site 1026

Chapel Hill, North Carolina, 27599, United States
Research Site 1027

Cromwell, Connecticut, 06416, United States
Research Site 1030

Philadelphia, Pennsylvania, 19104, United States
Research Site 1032

Chevy Chase, Maryland, 20815, United States
Research Site 1033

Topeka, Kansas, 66606, United States
Research Site 1034

Aurora, Colorado, 80045, United States
Research Site 1036

Pearland, Texas, 77584, United States
Research Site 1037

Scottsdale, Arizona, 85258, United States
Research Site 1039

Dothan, Alabama, 36305, United States
Research Site 1040

Inverness, Florida, 34452, United States
Research Site 1041

Rockwell, Texas, 75032, United States
Research Site 1042

Creve Coeur, Missouri, 63141, United States
Research Site 1043

Jackson, New Jersey, 08527, United States
Research Site 1045

Freehold, New Jersey, 07728, United States
Research Site 1048

Glenview, Illinois, 60026, United States
Research Site 1049

Miami, Florida, 33155, United States
Research Site 1101

Parkville, Victoria, 3010, Australia
Research Site 1102

Fitzroy, Victoria, 3065, Australia
Research Site 1103

South Brisbane, Queensland, 4101, Australia
Research Site 1106

Box Hill, Victoria, 3128, Australia
Research Site 1107

Woolloongabba, QLD 4102, Australia
Research Site 1107

Woolloongabba, Queensland, 4102, Australia
Research Site 1108

Newcastle, New South Wales, 02111, Australia
Research Site 1109

Murdoch, Western AUS, 6050, Australia
Research Site 1110

Maroochydore, Queensland, 4558, Australia
Research Site 1111

Maroochydore, QLD 4558, Australia
Research Site 1151

Leuven, VLG, 3000, Belgium
Research Site 1152

Bruges, 8310, Belgium
Research Site 1153

Tournai, 7500, Belgium
Research Site 1201

Warsaw, 04-501, Poland
Research Site 1202

Szczecin, 04-501, Poland
Research Site 1203

Warsaw, 00-189, Poland
Research Site 1204

Warsaw, 04-141, Poland
Research Site 1205

Tychy, 43-100, Poland
Research Site 1206

Warsaw, 02-781, Poland
Research Site 1207

Lodz, 90-752, Poland
Research Site 1252

Milan, Ca'Granada, 20122, Italy
Research Site 1253

Padua, IT, 35128, Italy
Research Site 1255

Roma, IT, 00168, Italy
Research Site 1256

Campobasso, IT, 86100, Italy
Research Site 1258

Verona, 37134, Italy
Research Site 1259

Pieve Emanuele, MI, 20072, Italy
Research Site 1302

Rotterdam, 3000, Netherlands
Research Site 1303

Maastricht, AZ, 6202, Netherlands
Research Site 1351

Tomelloso, 13700, Spain
Research Site 1352

Madrid, 28040, Spain
Research Site 1353

Madrid, 28006, Spain
Research Site 1354

Barcelona, 08022, Spain
Research Site 1402

Zurich, 8044, Switzerland
Research Site 1551

Whitechapel, London, E1 1BB, United Kingdom
Research Site 1553

London, Tooting, SW17 0GT, United Kingdom

Conditions

Explore the condition pages connected to this study.

EOSINOPHILIC ESOPHAGITIS (EOE)