Scientists probe resistance to targeted lung cancer drug

NCT ID NCT06247826

First seen May 10, 2026 · Last updated May 16, 2026 · Updated 3 times

Summary

This study looks at why some lung cancers with a specific gene change (EGFR exon 20 insertion) stop responding to the drug amivantamab. Researchers will collect blood and tumor samples from 30 patients when their disease gets worse. The goal is to find the genetic changes that cause resistance and help doctors choose better next treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • CH Bretagne Atlantique

    RECRUITING

    Vannes, 56017, France

    Contact Email: •••••@•••••

  • CHU Hôpital Nord

    RECRUITING

    Saint-Etienne, 42055, France

    Contact Email: •••••@•••••

    Contact

  • CHU La Réunion Site Nord

    RECRUITING

    Saint-Denis, 97411, France

    Contact Email: •••••@•••••

    Contact

  • Centre Hospitalier du Morvan

    RECRUITING

    Brest, 29200, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hôpital Charles Nicolle

    RECRUITING

    Rouen, 76031, France

    Contact Email: •••••@•••••

    Contact

  • Hôpital Cochin

    RECRUITING

    Paris, 75014, France

    Contact Email: •••••@•••••

  • Oncologie Institut Curie

    NOT_YET_RECRUITING

    Paris, 75005, France

    Contact Email: •••••@•••••

  • Oncologie Polyclinique Bordeaux Nord Aquitaine

    NOT_YET_RECRUITING

    Bordeaux, 33000, France

    Contact Email: •••••@•••••

  • Oncologie thoracique Hôpital Nord

    RECRUITING

    Marseille, 13915, France

    Contact Email: •••••@•••••

  • Oncologie, CLCC Dijon

    NOT_YET_RECRUITING

    Dijon, 21000, France

    Contact Email: •••••@•••••

  • Oncologie, Centre Antoine Lacassagne

    WITHDRAWN

    Nice, 06149, France

  • Pneumologie CH

    NOT_YET_RECRUITING

    Le Mans, 72000, France

    Contact Email: •••••@•••••

  • Pneumologie CHI Cornouaille

    NOT_YET_RECRUITING

    Quimper, 02900, France

    Contact Email: •••••@•••••

  • Pneumologie Centre Hospitalier

    NOT_YET_RECRUITING

    Pau, 64000, France

    Contact Email: •••••@•••••

  • Pneumologie Centre Hospitalier Intercommunal de Créteil

    RECRUITING

    Créteil, 94010, France

    Contact Email: •••••@•••••

    Contact

  • Pneumologie, CHU Grenoble

    RECRUITING

    Grenoble, 38043, France

    Contact Email: •••••@•••••

  • Pneumologie, Hôpital Mutualiste Resamut

    NOT_YET_RECRUITING

    Villeurbanne, 69100, France

    Contact Email: •••••@•••••

  • Pneumologie, Hôpital Tenon

    RECRUITING

    Paris, 75970, France

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.