New hope for hard-to-treat lung cancer: targeted therapy MK-1084 enters trial

NCT ID NCT07286149

First seen Jan 04, 2026 · Last updated May 14, 2026 · Updated 21 times

Summary

This study tests a new medicine called MK-1084 in people with advanced non-squamous non-small cell lung cancer that has a specific genetic change (KRAS G12C). The goal is to see if the drug is safe and can shrink tumors. About 190 adults who have already tried other treatments will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bradfordhill ( Site 0160)

    RECRUITING

    Santiago, Region M. de Santiago, 8420383, Chile

    Contact Phone: •••-•••-••••

  • Centro de Estudios Clínicos SAGA-CECSAGA ( Site 0162)

    RECRUITING

    Santiago, Region M. de Santiago, 7500653, Chile

    Contact Phone: •••-•••-••••

  • Clermont Oncology Center ( Site 0041)

    RECRUITING

    Clermont, Florida, 34711, United States

    Contact Phone: •••-•••-••••

  • Fundação Faculdade Regional de Medicina de São José do Rio Preto ( Site 0286)

    RECRUITING

    São José do Rio Preto, São Paulo, 15090-000, Brazil

    Contact Phone: •••-•••-••••

  • Fundação Pio XII - Hospital de Câncer de Barretos ( Site 0282)

    RECRUITING

    Barretos, São Paulo, 14784-400, Brazil

    Contact Phone: •••-•••-••••

  • Guangdong Provincial People s Hospital ( Site 0300)

    RECRUITING

    Guangzhou, Guangdong, 510120, China

    Contact Phone: •••-•••-••••

  • Hospital Clínic de Barcelona ( Site 0092)

    RECRUITING

    Barcelona, 08036, Spain

    Contact Phone: •••-•••-••••

  • Hospital Paulistano ( Site 0280)

    RECRUITING

    São Paulo, São Paulo, 01321001, Brazil

    Contact Phone: •••-•••-••••

  • Hospital Universitario Virgen Macarena ( Site 0093)

    RECRUITING

    Seville, 41009, Spain

    Contact Phone: •••-•••-••••

  • Severance Hospital, Yonsei University Health System ( Site 0080)

    RECRUITING

    Seoul, 03722, South Korea

    Contact Phone: •••-•••-••••

  • Shaare Zedek Medical Center ( Site 0186)

    RECRUITING

    Jerusalem, 9103102, Israel

    Contact Phone: •••-•••-••••

  • Sheba Medical Center ( Site 0180)

    RECRUITING

    Ramat Gan, 5265601, Israel

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.