Brain cell transplant could tame severe epilepsy

NCT ID NCT05135091

First seen Nov 01, 2025 · Last updated Apr 26, 2026 · Updated 26 times

Summary

This study tests a one-time injection of special nerve cells (NRTX-1001) into the brain for people with drug-resistant epilepsy. The cells release a calming chemical to reduce seizures. Researchers will check safety and how well it works compared to a sham procedure in 88 adults.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Atrium Health

    RECRUITING

    Charlotte, North Carolina, 28204, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Atrium Wake Forest Baptist

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Banner-University of Arizona Medical Center Tucson Comprehensive Epilepsy Program

    RECRUITING

    Tucson, Arizona, 85724-5023, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dartmouth Hitchcock Medical Center/ Department of Neurology

    RECRUITING

    Lebanon, New Hampshire, 03756, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Duke University Hospital

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • George Washington University

    RECRUITING

    Washington D.C., District of Columbia, 20037, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hofstra Northwell Comprehensive Epilepsy Center

    RECRUITING

    Great Neck, New York, 11021, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mayo Clinic Arizona Epilepsy Center

    RECRUITING

    Phoenix, Arizona, 85054, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • NYU Langone Comprehensive Epilepsy Center

    RECRUITING

    New York, New York, 10016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Ochsner Clinic Foundation

    RECRUITING

    New Orleans, Louisiana, 70121, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oregon Health and Science University

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Rush University Medical Center

    RECRUITING

    Chicago, Illinois, 60612, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • SUNY Upstate Medical University

    RECRUITING

    Syracuse, New York, 13210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Stanford University

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Thomas Jefferson University Hospital

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UC Irvine Medical Center

    RECRUITING

    Orange, California, 92868, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UTHealth Houston

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Arkansas for Medical Sciences

    RECRUITING

    Little Rock, Arkansas, 72205, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California Davis

    RECRUITING

    Sacramento, California, 95817, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California San Diego

    RECRUITING

    San Diego, California, 92037, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Colorado Anschutz Medical Campus

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Iowa Health Care

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Miami

    RECRUITING

    Miami, Florida, 33136, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Southern California Keck Hospital

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Utah Health

    RECRUITING

    Salt Lake City, Utah, 84108, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Washington Regional Epilepsy Center

    RECRUITING

    Seattle, Washington, 98104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Wayne State University/Detroit Medical Center Comprehensive Epilepsy Program

    RECRUITING

    Detroit, Michigan, 48201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.