New pill aims to slow vision loss in rare usher syndrome

NCT ID NCT04355689

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study tests whether NPI-001 tablets can safely slow or stop vision loss in people with Usher syndrome, a rare genetic condition that causes blindness and hearing loss. About 49 adults will take either the study drug or a placebo for 24 months. The main goal is to see if the drug helps preserve retinal sensitivity.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CERA

    Melbourne, Australia

  • Lions Eye Institute

    Perth, Australia

  • Queensland Eye Institute

    Brisbane, Australia

  • Sydney Eye Hospital / Save Sight Institute

    Sydney, Australia

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