New pill aims to slow vision loss in rare usher syndrome

NCT ID NCT04355689

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study tests whether NPI-001 tablets can safely slow or stop vision loss in people with Usher syndrome, a rare genetic condition that causes blindness and hearing loss. About 49 adults will take either the study drug or a placebo for 24 months. The main goal is to see if the drug helps preserve retinal sensitivity.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

retinitis pigmentosa Usher syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CERA

    Melbourne, Australia

  • Lions Eye Institute

    Perth, Australia

  • Queensland Eye Institute

    Brisbane, Australia

  • Sydney Eye Hospital / Save Sight Institute

    Sydney, Australia