New hope for hard-to-treat ovarian cancer: experimental combo shows promise

NCT ID NCT07109414

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 23 times

Summary

This study tests whether adding the experimental drug NP-G2-044 (Prilukae) to standard chemotherapy (PLD) can help people with platinum-resistant ovarian cancer, a type that has stopped responding to initial treatments. About 380 participants will receive either the combination or PLD alone. The goal is to see if the combo can shrink tumors or delay cancer growth, but it is not expected to be a cure.

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Contacts and locations

Locations

  • HonorHealth Cancer Care

    Phoenix, Arizona, 85016, United States

  • Optimum Clinical Research Group, LLC

    Albuquerque, New Mexico, 87109, United States

  • Trials365

    Shreveport, Louisiana, 71133, United States

  • University Of Wisconsin Carbone Cancer Center

    Madison, Wisconsin, 53792-9988, United States

  • University of Pennsylvania Health System, Perelman Center for Advanced Medicine

    Philadelphia, Pennsylvania, 19104-5127, United States

  • Utah Cancer Specialists

    Salt Lake City, Utah, 84106, United States

Conditions

Explore the condition pages connected to this study.