New hope for blood cancer patients: experimental drug enters human trials

NCT ID NCT07226843

First seen Nov 12, 2025 · Last updated May 15, 2026 · Updated 20 times

Summary

This study is testing an experimental drug called LY4584180 in adults with certain blood cancers (like lymphoma) that have not improved after at least two prior treatments. The main goals are to check the drug's safety, how the body processes it, and whether it can shrink tumors. About 460 participants will take part, and the study lasts around 9 months or longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AIDPORT Sp. z o.o.

    NOT_YET_RECRUITING

    Skorzewo, 60-185, Poland

  • Baylor College of Medicine

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

  • CHU Bordeaux - Hopital Haut-Leveque - Centre Francois Magendie

    NOT_YET_RECRUITING

    Pessac, 33604, France

  • CHU de Nantes - Hotel-Dieu

    NOT_YET_RECRUITING

    Nantes, 44093, France

  • Cancer Institute Hospital of JFCR

    NOT_YET_RECRUITING

    Tokyo, 135-8550, Japan

  • Charite Universitaetsmedizin Berlin

    NOT_YET_RECRUITING

    Berlin, 10117, Germany

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

  • Colorado Blood Cancer Institute

    RECRUITING

    Denver, Colorado, 80218, United States

  • Columbia University

    NOT_YET_RECRUITING

    New York, New York, 10032, United States

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Derriford Hospital

    NOT_YET_RECRUITING

    Plymouth, PL6 8DH, United Kingdom

  • Emory University Hospital

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Florida Cancer Specialists - Sarasota

    RECRUITING

    Sarasota, Florida, 34236, United States

  • Froedtert Hospital and the Medical College of Wisconsin

    NOT_YET_RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • HCL Centre Hospitalier Lyon Sud

    NOT_YET_RECRUITING

    Pierre-Bénite, 69495, France

  • IRCCS Azienda Ospedaliero-Universitaria di Bologna - Policlinico di Sant Orsola

    NOT_YET_RECRUITING

    Bologna, 40138, Italy

  • Institut Catala d'Oncologia - L'Hospitalet

    NOT_YET_RECRUITING

    Barcelona, 08908, Spain

  • Institut Curie

    NOT_YET_RECRUITING

    Paris, 75005, France

  • Instytut Hematologii i Transfuzjologii w Warszawie

    NOT_YET_RECRUITING

    Warsaw, 02-776, Poland

  • Istituto Europeo di Oncologia

    NOT_YET_RECRUITING

    Milan, 20141, Italy

  • King's College Hospital

    NOT_YET_RECRUITING

    London, SE5 9RS, United Kingdom

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic - Rochester

    NOT_YET_RECRUITING

    Rochester, Minnesota, 55905, United States

  • Mayo Clinic - Scottsdale

    NOT_YET_RECRUITING

    Scottsdale, Arizona, 85259, United States

  • National Cancer Center Hospital East

    NOT_YET_RECRUITING

    Chiba, 277-8577, Japan

  • Nottingham City Hospital

    NOT_YET_RECRUITING

    Nottingham, NG5 1PB, United Kingdom

  • Oncopole Claudius Regaud

    NOT_YET_RECRUITING

    Toulouse, 31059, France

  • Oregon Health & Science University (OHSU)

    NOT_YET_RECRUITING

    Portland, Oregon, 97239, United States

  • Pratia MCM Krakow

    NOT_YET_RECRUITING

    Krakow, 30-727, Poland

  • Pratia Onkologia Katowice

    NOT_YET_RECRUITING

    Katowice, 40-519, Poland

  • Sarah Cannon Research Institute

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • South Texas Accelerated Research Therapeutics (START) Madrid - Hospital Fundacion Jimenez Diaz

    NOT_YET_RECRUITING

    Madrid, 28040, Spain

  • Texas Oncology - DFW (Sammons CC)

    NOT_YET_RECRUITING

    Dallas, Texas, 75246, United States

  • The Ohio State University (OSU)

    RECRUITING

    Columbus, Ohio, 43210, United States

  • The Royal Marsden NHS Foundation Trust

    NOT_YET_RECRUITING

    London, SW3 6JJ, United Kingdom

  • Universitaetsklinikum Essen

    NOT_YET_RECRUITING

    Essen, 45147, Germany

  • Universitaetsklinikum Frankfurt - Klinikum der Johann Wolfgang Goethe Universitaet

    NOT_YET_RECRUITING

    Frankfurt am Main, 60590, Germany

  • Universitaetsklinikum Koeln (AoeR)

    NOT_YET_RECRUITING

    Cologne, 50937, Germany

  • University Hospital Southampton NHS Foundation Trust

    NOT_YET_RECRUITING

    Southampton, SO16 6YD, United Kingdom

  • University of California, Los Angeles (UCLA) - Medical Center

    NOT_YET_RECRUITING

    Los Angeles, California, 90059, United States

  • University of California, San Francisco (UCSF) - Helen Diller Family Comprehensive Cancer Center

    NOT_YET_RECRUITING

    San Francisco, California, 94158, United States

  • University of Miami - Sylvester Cancer Center

    NOT_YET_RECRUITING

    Miami, Florida, 33136, United States

  • University of Rochester

    RECRUITING

    Rochester, New York, 14618, United States

  • University of Washington - Fred Hutchinson Cancer Center (Seattle Cancer Care Alliance)

    NOT_YET_RECRUITING

    Seattle, Washington, 98195, United States

  • Vanderbilt University Medical Center

    NOT_YET_RECRUITING

    Nashville, Tennessee, 37212, United States

Conditions

Explore the condition pages connected to this study.