Can a blood pressure drug help kids with menkes disease?
NCT ID NCT07398508
First seen Jun 27, 2026 · Last updated Jul 21, 2026 · Updated 2 times
Summary
This study tests whether Northera (droxidopa) is safe and can improve symptoms like dizziness, fainting, and low blood pressure in children aged 7 to 17 with Menkes disease. Six to ten participants will receive either the drug or a placebo in two four-week periods, with careful dose adjustments. The goal is to see if the drug raises blood pressure and improves quality of life.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Northera (droxidopa)
- What this could lead to
- If it works, this could point toward a treatment that improves daily life for children with Menkes disease who have symptoms like dizziness and fainting.
- What could go wrong
- This is a very small early-phase trial with only 6 participants, so results may not apply broadly. The drug may not work better than placebo, and side effects are unknown in this group.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Vagelos College of Physicians and Surgeons, Columbia University
RECRUITINGNew York, New York, 10032, United States
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