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No x-rays needed: new light-based test may spot bowel slowdowns in kids

NCT ID NCT06911749

Recruiting now Diagnosis Sponsor: Dr. med. Sonja Diez Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a new way to measure how fast food moves through the gut in children with chronic constipation or other bowel emptying disorders. Instead of X-rays, it uses a special light-based imaging technique (MSOT) combined with a safe dye (ICG) and MRI scans. The goal is to find which part of the bowel is slow, so doctors can choose the best treatment. The study will include 20 children and a small group of healthy adults.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Indocyanine Green (ICG) contrast agent
What this could lead to
If successful, this could provide a safer, radiation-free way to diagnose bowel movement problems in children and help guide personalized treatment.
What could go wrong
This is a small, early-phase study with only 20 participants, so results may not apply to all children. The MSOT technique is not yet standard and may not work as expected.

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Conditions

The condition(s) this trial relates to.

constipation disorder Hirschsprung disease intestinal motility disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC CONSTIPATION HIRSCHSPRUNGS DISEASE INTESTINAL TRANSIT DISORDER SLOW TRANSIT CONSTIPATION

Contacts and locations

Locations

  • University Hospital Erlangen, Pediatric Surgery

    RECRUITING

    Erlangen, Bavaria, 91054, Germany

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