Immune cells take on childhood cancer in new trial

NCT ID NCT02573896

First seen Mar 24, 2026 · Last updated Apr 28, 2026 · Updated 2 times

Summary

This early-phase trial tests a new treatment for children with neuroblastoma that has come back or not responded to standard therapy. It uses the child's own natural killer (NK) cells, grown in a lab, combined with an antibody drug (dinutuximab) and sometimes another drug (lenalidomide) to boost the immune attack on cancer cells. The main goals are to find the safest dose and see if it's possible to produce enough NK cells for treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus

    Atlanta, Georgia, 30322, United States

  • C.S Mott Children's Hospital

    Ann Arbor, Michigan, 48109, United States

  • Children's Hospital Los Angeles

    Los Angeles, California, 90027-0700, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104-4318, United States

  • Childrens Hospital Boston, Dana-Farber Cancer Institute.

    Boston, Massachusetts, 02115, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229-3039, United States

  • Cook Children's Healthcare System

    Fort Worth, Texas, 76104, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

  • Seattle Children's Hospital

    Seattle, Washington, 98105, United States

  • UCSF Helen Diller Family Comprehensive Cancer Center

    San Francisco, California, 94115, United States

  • University of Chicago Comer Children's Hospital

    Chicago, Illinois, 60637, United States

Conditions

Explore the condition pages connected to this study.