New shot-based immunotherapy combo tested for advanced lung cancer

NCT ID NCT06946797

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 27 times

Summary

This study tests two different dosing schedules of a subcutaneous (under-the-skin) form of the immunotherapy drug nivolumab, given together with intravenous ipilimumab and chemotherapy. The goal is to find the best dosing regimen for people with previously untreated metastatic or recurrent non-small cell lung cancer. About 76 participants will be enrolled, and the study will measure drug levels in the blood as well as safety and side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • "Theagenio" Cancer Hospital of Thessaloniki

    RECRUITING

    Thessaloniki, Kentrikí Makedonía, 540 07, Greece

    Contact Phone: •••-•••-••••

  • Alaska Oncology and Hematology

    RECRUITING

    Anchorage, Alaska, 99508, United States

    Contact Phone: •••-•••-••••

  • Azienda Ospedaliera Universitaria Careggi

    RECRUITING

    Florence, Tuscany, 50134, Italy

    Contact Phone: •••-•••-••••

  • Azienda Ospedaliero Universitaria Maggiore della Carità

    RECRUITING

    Novara, 28100, Italy

    Contact Phone: •••-•••-••••

  • Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII

    RECRUITING

    Bergamo, Lombardy, 24127, Italy

    Contact Phone: •••-•••-••••

  • Beacon Cancer Care

    RECRUITING

    Post Falls, Idaho, 83854, United States

    Contact Phone: •••-•••-••••

  • Bradfordhill

    RECRUITING

    Santiago, Santiago Metropolitan, 8420383, Chile

    Contact Phone: •••-•••-••••

  • Cancercare Rondebosch Oncology

    RECRUITING

    Rondebosch, Western Cape, 7700, South Africa

    Contact Phone: •••-•••-••••

  • Centre Georges François Leclerc

    RECRUITING

    Dijon, Côte-d'Or, 21079, France

    Contact Phone: •••-•••-••••

  • Centrul de Diagnostic si Tratament Provita

    RECRUITING

    Bucharest, 020335, Romania

    Contact Phone: •••-•••-••••

  • Centrul de Oncologie "Sfântul Nectarie"

    RECRUITING

    Craiova, Dolj, 200542, Romania

    Contact Phone: •••-•••-••••

  • Fundação Pio XII - Hospital de Câncer de Barretos

    RECRUITING

    Barretos, São Paulo, 14784400, Brazil

    Contact Phone: •••-•••-••••

  • Groupe hospitalier Paris saint Joseph

    RECRUITING

    Paris, Île-de-France Region, 75014, France

    Contact Phone: •••-•••-••••

  • Hospital Luxemburgo

    RECRUITING

    Belo Horizonte, Minas Gerais, 30380-490, Brazil

    Contact Phone: •••-•••-••••

  • Hospital Sirio Libanes

    RECRUITING

    Brasília, Federal District, 70200-730, Brazil

    Contact Phone: •••-•••-••••

  • Hospital de Clinicas de Porto Alegre

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 90035-903, Brazil

    Contact Phone: •••-•••-••••

  • Hôpital Foch

    RECRUITING

    Suresnes, Hauts-de-Seine, 92151, France

    Contact Phone: •••-•••-••••

  • IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori"

    RECRUITING

    Meldola, Emilia-Romagna, 47014, Italy

    Contact Phone: •••-•••-••••

  • Icesp - Instituto Do Câncer Do Estado de São Paulo

    RECRUITING

    São Paulo, 01246-000, Brazil

    Contact Phone: •••-•••-••••

  • Institutul Oncologic Bucuresti "Prof. Dr. Alexandru Trestioreanu"

    RECRUITING

    Bucharest, Bucharest, 022328, Romania

    Contact Phone: •••-•••-••••

  • Institutul Oncologic Cluj

    RECRUITING

    Cluj-Napoca, 400015, Romania

    Contact Phone: •••-•••-••••

  • Institutul Regional de Oncologie

    RECRUITING

    Iași, 700483, Romania

    Contact Phone: •••-•••-••••

  • Instytut Centrum Zdrowia Matki Polki

    RECRUITING

    Lodz, Łódź Voivodeship, 93-338, Poland

    Contact Phone: •••-•••-••••

  • Lehigh Valley Health Network

    RECRUITING

    Allentown, Pennsylvania, 18103, United States

    Contact Phone: •••-•••-••••

  • Local Institution - 0009

    NOT_YET_RECRUITING

    Sandton, GP, 2196, South Africa

    Contact

  • Local Institution - 0022

    WITHDRAWN

    Puebla City, 72424, Mexico

  • Local Institution - 0024

    WITHDRAWN

    México, 06700, Mexico

  • Local Institution - 0025

    WITHDRAWN

    Guadalajara, Jalisco, 44630, Mexico

  • Local Institution - 0027

    WITHDRAWN

    Mérida, Yucatán, 97070, Mexico

  • Local Institution - 0047

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact

  • Local Institution - 0058

    WITHDRAWN

    Monterrey, Nuevo León, 64460, Mexico

  • Local Institution - 0063

    NOT_YET_RECRUITING

    Boise, Idaho, 83702, United States

    Contact

  • Local Institution - 0066

    WITHDRAWN

    Pretoria, Gauteng, 0181, South Africa

  • Local Institution - 0070

    WITHDRAWN

    Adana, 01140, Turkey (Türkiye)

  • Local Institution - 0071

    WITHDRAWN

    Istanbul, 34214, Turkey (Türkiye)

  • Local Institution - 0072

    WITHDRAWN

    Ankara, 06010, Turkey (Türkiye)

  • Local Institution - 0088

    NOT_YET_RECRUITING

    Newport Beach, California, 92663, United States

    Contact

  • Mazowiecki Szpital Onkologiczny

    RECRUITING

    Warsaw, Masovian Voivodeship, 03-411, Poland

    Contact Phone: •••-•••-••••

  • MetroHealth Medical Center

    RECRUITING

    Cleveland, Ohio, 44109, United States

    Contact Phone: •••-•••-••••

  • P.O. "S. Maria della Misericordia" Azienda Sanitaria Universitaria Friuli Centrale

    RECRUITING

    Udine, Friuli Venezia Giulia, 33100, Italy

    Contact Phone: •••-•••-••••

  • SC Radiotherapy Center Cluj SRL

    RECRUITING

    Florești, Cluj, 407280, Romania

    Contact Phone: •••-•••-••••

  • Saint Alphonsus Regional Medical Center

    RECRUITING

    Boise, Idaho, 83706, United States

    Contact Phone: •••-•••-••••

  • Szpital Specjalistyczny w Prabutach Spolka z o.o.

    RECRUITING

    Prabuty, Pomeranian Voivodeship, 82-550, Poland

    Contact Phone: •••-•••-••••

  • Thoracic General Hospital of Athens "I Sotiria"

    RECRUITING

    Athens, Attikí, 115 27, Greece

    Contact Phone: •••-•••-••••

  • USC/Norris Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90033, United States

    Contact Phone: •••-•••-••••

  • University General Hospital "ATTIKON" - General Hospital of West Attica "H AGIA VARVARA"

    RECRUITING

    Chaïdári, Attikí, 12462, Greece

    Contact Phone: •••-•••-••••

  • University General Hospital of Larissa

    RECRUITING

    Larissa, Thessalía, 41110, Greece

    Contact Phone: •••-•••-••••

  • Wits Clinical Research

    RECRUITING

    Soweto, Gauteng, 2013, South Africa

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.