Immunotherapy before surgery shows promise for oral cancer

NCT ID NCT07514767

First seen Apr 09, 2026 · Last updated May 14, 2026 · Updated 5 times

Summary

This study tests whether giving the immunotherapy drug nivolumab before surgery can shrink advanced oral cancer tumors. About 60 adults with resectable oral squamous cell carcinoma will receive nivolumab, then have surgery. Researchers will also look for biomarkers in lymph nodes that predict response. The goal is to improve outcomes and understand who benefits most.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Karolinska University Hospital, Head-, neck-, lung- and skin cancer, Theme Cancer

    Stockholm, Sweden

    Contact

Conditions

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