Breathing battle: which oxygen method saves more lives after ICU extubation?

NCT ID NCT05686850

Recruiting now Disease control Sponsor: Poitiers University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at two ways to help ICU patients who struggle to breathe after their breathing tube is taken out. About 670 adults will be randomly assigned to receive either a non-invasive ventilation mask alternating with high-flow nasal oxygen, or high-flow nasal oxygen alone. The goal is to see which approach lowers the chance of death within 28 days.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST EXTUBATION RESPIRATORY FAILURE

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

André Mignot Hospital
RECRUITING

Le Chesnay, France
Angers University Hospital
RECRUITING

Angers, France
Bordeaux University Hospital
WITHDRAWN

Bordeaux, France
Brest University Hospital
RECRUITING

Brest, France
Clermont-Ferrand University Hospital
RECRUITING

Clermont-Ferrand, France
Complejo Hospitalario Universitario de Toledo
TERMINATED

Toledo, Spain
Cèdres Clinic
RECRUITING

Cornebarrieu, France
Dax Hospital
WITHDRAWN

Dax, France
Emile Muller Hospital
RECRUITING

Mulhouse, France
Erasme Hospital
RECRUITING

Brussels, Belgium
Felix Guyon Hospital
TERMINATED

Saint-Denis, Reunion
Fleyriat Hospital
RECRUITING

Bourg-en-Bresse, France
Foch Hospital
RECRUITING

Suresnes, France
Francois Mitterrand Hospital
RECRUITING

Dijon, France
Grenoble University Hospital
RECRUITING

Grenoble, France
Henri Duffaut Hospital
RECRUITING

Avignon, France
Henri Mondor Hospital
RECRUITING

Aurillac, France
Henri Mondor Hospital
RECRUITING

Créteil, France
Hospital Universitari de Bellvitge
NOT_YET_RECRUITING

L'Hospitalet de Llobregat, Spain
Hospital Universitario Central de Asturias
NOT_YET_RECRUITING

Oviedo, Spain
Hospital de La Santa Creu I Sant Pau
NOT_YET_RECRUITING

Barcelona, Spain
La Pitié Salpêtrière Hospital
RECRUITING

Paris, France
La Rochelle Hospital
RECRUITING

La Rochelle, France
La Timone Hospital
RECRUITING

Marseille, France
Le Mans Hospital
RECRUITING

Le Mans, France
Lens Hospital
RECRUITING

Lens, France
Lille University Hospital
RECRUITING

Lille, France
Limoges University Hospital
RECRUITING

Limoges, France
Louis Mourier Hospital
RECRUITING

Colombes, France
Mont de Marsan Hospital
WITHDRAWN

Mont-de-Marsan, France
Moulins-Yzeure Hospital
RECRUITING

Moulins, France
Nantes University Hospital
RECRUITING

Nantes, France
Nice University Hospital
RECRUITING

Nice, France
Nord-Franche-Comté Hospital
RECRUITING

Belfort, France
Orléans University Hospital
RECRUITING

Orléans, France
Pau Hospital
RECRUITING

Pau, France
Pierre Zobda Quitman Hospital
RECRUITING

Fort-de-France, Martinique
Poitiers University Hospital
RECRUITING

Poitiers, France
Rennes University Hospital
RECRUITING

Rennes, France
Rouen University Hospital
RECRUITING

Rouen, France
Saint Joseph Saint Luc Hospital
RECRUITING

Lyon, France
Saint Nazaire Hospital
RECRUITING

Saint-Nazaire, France
Saintes Hospital
RECRUITING

Saintes, France
Tours University Hospital
RECRUITING

Tours, France
Vannes Hospital
RECRUITING

Vannes, France
Vendée Hospital
RECRUITING

La Roche-sur-Yon, France
Victor Dupouy Hospital
RECRUITING

Argenteuil, France