New drug aims to protect unborn babies from dangerous bleeding disorder

NCT ID NCT06533098

First seen Nov 01, 2025 · Last updated May 03, 2026 · Updated 26 times

Summary

This study tests a new medicine called nipocalimab against a standard treatment (IVIG) in 50 pregnant women who have had a previous pregnancy affected by FNAIT, a condition where the mother's immune system attacks the baby's platelets. The goal is to see if nipocalimab can better prevent severe bleeding or death in the fetus or newborn. Participants will receive either nipocalimab or IVIG during their current pregnancy.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Advocate Children's Hospital

    RECRUITING

    Park Ridge, Illinois, 60068, United States

  • Birmingham Women's Hospital

    RECRUITING

    Birmingham, B15 2TG, United Kingdom

  • Childrens Hospital Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

  • Hospital of the University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • Instytut Centrum Zdrowia Matki Polki

    RECRUITING

    Lodz, 93 338, Poland

  • Instytut Matki i Dziecka

    RECRUITING

    Warsaw, 01 211, Poland

  • John Radcliffe Hospital

    RECRUITING

    Oxford, OX3 9DU, United Kingdom

  • Leiden University Medical Center

    RECRUITING

    Leiden, 2333 ZA, Netherlands

  • Liverpool Women's NHS Foundation Trust - Liverpool Women's Hospital

    RECRUITING

    Liverpool, L8 7SS, United Kingdom

  • Medical University Vienna

    RECRUITING

    Vienna, 1090, Austria

  • Medizinische Hochschule Hannover

    RECRUITING

    Hanover, 30625, Germany

  • Medizinische Universitaet Graz

    RECRUITING

    Graz, 8036, Austria

  • Oregon Health And Science University

    RECRUITING

    Portland, Oregon, 97239, United States

  • Panstwowy Instytut Medyczny MSWiA w Warszawie

    RECRUITING

    Warsaw, 02 507, Poland

  • Queen Charlotte's and Chelsea Hospital

    RECRUITING

    London, W12 0HS, United Kingdom

  • The University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35205, United States

  • UC Davis School of Medicine

    RECRUITING

    Sacramento, California, 95817, United States

  • Universitaetsklinikum Giessen und Marburg GmbH

    RECRUITING

    Giessen, 35392, Germany

  • Universitaetsklinikum Tuebingen

    RECRUITING

    Tübingen, 72076, Germany

  • Universitatsklinikum Jena

    RECRUITING

    Jena, 07747, Germany

  • University of Cincinnati

    RECRUITING

    Cincinnati, Ohio, 45267, United States

  • University of Iowa Hospital and Clinics

    RECRUITING

    Iowa City, Iowa, 52242, United States

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

  • University of Texas Medical Branch

    RECRUITING

    Galveston, Texas, 77555, United States

Conditions

Explore the condition pages connected to this study.