New drug trial offers hope for debilitating Muscle-Weakening disease

NCT ID NCT04951622

Recruiting now Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

Summary

This study is testing an investigational drug called nipocalimab to see if it can reduce symptoms and improve daily life for adults with generalized myasthenia gravis (gMG), a chronic autoimmune disease that causes severe muscle weakness. About 199 participants will be randomly assigned to receive either the drug or a placebo to compare effectiveness and safety. The main goal is to see if the drug helps with common symptoms like trouble talking, chewing, swallowing, and breathing over a 24-week period.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AZ Sint Jan Brugge Oostende AV
RECRUITING

Bruges, 8000, Belgium
AZ Sint-Lucas
RECRUITING

Ghent, 9000, Belgium
Aalborg University Hospital
COMPLETED

Aalborg, 9000, Denmark
Augusta University
COMPLETED

Augusta, Georgia, 30912-3125, United States
Azienda Ospedaliera Univ.- Università Degli studi della Campania - Luigi Vanvitelli
RECRUITING

Naples, 80138, Italy
Azienda ospedaliera Sant'Andrea di Roma- Università di Roma La Sapienza
COMPLETED

Roma, 00189, Italy
Beijing Hospital
RECRUITING

Beijing, 100730, China
Beijing Tiantan Hospital, Capital Medical University
RECRUITING

Beijing, 100050, China
CHU Grenoble
COMPLETED

Grenoble, 38043, France
Care Access Research
RECRUITING

Pasadena, California, 91101, United States
Centrum Medyczne NeuroProtect
RECRUITING

Warsaw, 01-684, Poland
Centrum Neurologii Klinicznej Krakowska Akademia Neurologii
RECRUITING

Krakow, 31 505, Poland
Chiba University Hospital
COMPLETED

Chiba, 260 8677, Japan
China Medical University Hospital
COMPLETED

Taichung, 40447, Taiwan
Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44145, United States
Cliniques Universitaires Saint Luc
RECRUITING

Brussels, 1200, Belgium
Consultorio Dr. Miguel Cortes
RECRUITING

Cuernavaca, 62448, Mexico
DKD HELIOS Klinik Wiesbaden, Fachbereich Neurologie
COMPLETED

Wiesbaden, 65191, Germany
Duke University School of Medicine
RECRUITING

Durham, North Carolina, 27710, United States
FM Clinical Research, LLC South Florida Neurology Associates, P. A.
RECRUITING

Boca Raton, Florida, 33487, United States
Fakultni nemocnice Brno
COMPLETED

Brno, 625 00, Czechia
Fondazione Istituto G. Giglio
RECRUITING

Cefalù, 90015, Italy
Fujian Medical University Union Hospital
COMPLETED

Fuzhou, 350001, China
General Hanamaki Hospital
RECRUITING

Hanamaki, 025-0082, Japan
Gold Coast University Hospital
RECRUITING

Southport, 4215, Australia
Hiroshima University Hospital
RECRUITING

Hiroshima, 734 8551, Japan
Hokkaido Medical Center
RECRUITING

Sapporo, 063 0005, Japan
HonorHealth Neurology
COMPLETED

Scottsdale, Arizona, 85251, United States
Hopital PASTEUR
RECRUITING

Provence-Alpes-Côte d'Azur, 06000, France
Hopital PASTEUR
COMPLETED

Provence-Alpes-Côte d'Azur, 06000, France
Hopital Pierre Wertheimer
RECRUITING

Bron, 69500, France
Hopital de la Pitie Salpetriere
RECRUITING

Paris, 75013, France
Hosp Clinic de Barcelona
RECRUITING

Barcelona, 8036, Spain
Hosp Univ Vall D Hebron
RECRUITING

Barcelona, 08035, Spain
Hosp. Gral. Univ. de Alicante
RECRUITING

Alicante, 03010, Spain
Hosp. Univ. I Politecni La Fe
RECRUITING

Valencia, 46026, Spain
Hosp. Univ. de Basurto
RECRUITING

Bilbao, 48013, Spain
Hosp. Virgen Del Rocio
COMPLETED

Seville, 41013, Spain
Hosp. Virgen Macarena
RECRUITING

Seville, 41009, Spain
Hosp. de La Santa Creu I Sant Pau
RECRUITING

Barcelona, 08025, Spain
Hospital Civil de Guadalajara Fray Antonio Alcalde
RECRUITING

Guadalajara, 44280, Mexico
Huashan Hospital Fudan University
RECRUITING

Shanghai, 200040, China
Hyogo College of Medicine Hospital
RECRUITING

Nishinomiya-Shi, 663-8501, Japan
IRCCS C. Mondino, Istituto Neurologico Nazionale, Fondazione
RECRUITING

Pavia, 27100, Italy
Istituto Neurologico Carlo Besta
RECRUITING

Milan, 20133, Italy
Iwate Medical University Hospital
RECRUITING

Morioka, 020-8505, Japan
Kagawa University Hospital
COMPLETED

Kita Gun, 761 0793, Japan
Karlstad Central Hospital
COMPLETED

Karlstad, 651 85, Sweden
Karolinska Universitetssjukhuset Solna
RECRUITING

Stockholm, 171 76, Sweden
Kumamoto University Hospital
COMPLETED

Kumamoto, 860-8556, Japan
Kyungpook National University Chilgok Hospital
RECRUITING

Daegu, 41404, South Korea
Kyungpook National University Hospital
COMPLETED

Daegu, 41944, South Korea
Lahey Hospital & Medical Center
COMPLETED

Burlington, Massachusetts, 01805, United States
McGill University
COMPLETED

Montreal, Quebec, H3A 2B4, Canada
Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States
Medsol Clinical Research Center Inc
RECRUITING

Port Charlotte, Florida, 33952, United States
Melbourne Neurology Group
COMPLETED

North Melbourne, 3051, Australia
NZOZ Wielospecjalistyczna Poradnia Lekarska 'Synapsis'
RECRUITING

Katowice, 40-123, Poland
National Hospital Organization Nagoya Medical Center
COMPLETED

Nagoya, 460-0001, Japan
National Hospital Organization Sendai Medical Center
RECRUITING

Sendai, 983-8520, Japan
NeuroCure Clinical Research Center
RECRUITING

Berlin, 10117, Germany
Neurocentrum Bydgoszcz Sp Z O O
RECRUITING

Bydgoszcz, 85 796, Poland
Neurologie a rehabilitace Skopalíkova
RECRUITING

Brno, 615 00, Czechia
Neuromuscular Research Center and Clinic
RECRUITING

Paradise Valley, Arizona, 85028, United States
Niigata City General Hospital
RECRUITING

Niigata, 950-1197, Japan
Policlinico Universitario Agostino Gemelli
RECRUITING

Roma, 168, Italy
Prywatny Gabinet Lekarski
RECRUITING

Lublin, 20 093, Poland
Pusan National University Hospital
RECRUITING

Busan, 49241, South Korea
Qianfoshan hospital of Shandong Province
RECRUITING

Jinan, 250014, China
Qilu Hospital of Shandong University
COMPLETED

Jinan, 250014, China
Rigshospitalet
COMPLETED

København Ø, 2100, Denmark
Sapporo Medical University Hospital
COMPLETED

Sapporo, 0608556, Japan
Severance Hospital Yonsei University Health System
RECRUITING

Seoul, 120-752, South Korea
Shin Kong Wu Ho Su Memorial Hospital
RECRUITING

Taipei, 111, Taiwan
Sir Run Run Shaw Hospital Zhejiang University School of Medicine
COMPLETED

Hangzhou, 310020, China
St Marianna University Hospital
RECRUITING

Kawasaki Shi, 216 8511, Japan
St. Elizabeth Medical Center
COMPLETED

Boston, Massachusetts, 02135, United States
Stanford University
COMPLETED

Palo Alto, California, 94304, United States
Taipei Veterans General Hospital
RECRUITING

Taipei, 11217, Taiwan
Teikyo University Hospital
RECRUITING

Itabashi Ku, 173 8606, Japan
The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
RECRUITING

Guangzhou, 510405, China
The First Bethune Hospital of Jilin University
RECRUITING

Changchun, 130021, China
The Ohio State University
COMPLETED

Columbus, Ohio, 43210, United States
The Ottawa Hospital Research Institute
RECRUITING

Ottawa, Ontario, K1Y 4E9, Canada
The Second Affiliated Hospital of Air Force Medical University - Tangdu Hospital
RECRUITING

Xi'an, 710038, China
Tianjin Medical University General Hospital
RECRUITING

Tianjin, 300052, China
Tokushima University Hospital
COMPLETED

Tokushima, 770-8503, Japan
Tokyo Medical University Hospital
COMPLETED

Tokyo, 160-0023, Japan
Toronto General Hospital
RECRUITING

Toronto, Ontario, M5G 2C4, Canada
U.O.P.I. di Psichiatria
COMPLETED

Catania, 95100, Italy
ULB Hôpital Erasme
RECRUITING

Anderlecht, 1070, Belgium
UT Southwestern Medical Center
COMPLETED

Dallas, Texas, 75390, United States
Universitaetsklinikum Leipzig
COMPLETED

Leipzig, 04103, Germany
Universitatsklinikum Schleswig Holstein Campus Lubeck
COMPLETED

Lübeck, 23538, Germany
Universitatsklinikum Ulm
COMPLETED

Ulm, 89081, Germany
Universitatsmedizin Gottingen
COMPLETED

Göttingen, 37075, Germany
University Hospitals Leuven
RECRUITING

Leuven, 3000, Belgium
University of Cincinnati
COMPLETED

Cincinnati, Ohio, 45219, United States
University of Colorado Anschutz Medical Campus
RECRUITING

Aurora, Colorado, 80045, United States
University of Florida Health Jacksonville
COMPLETED

Jacksonville, Florida, 32209, United States
University of Kansas Medical Center
RECRUITING

Kansas City, Kansas, 66160, United States
University of South Florida
RECRUITING

Tampa, Florida, 33612, United States
University of Southern California
COMPLETED

Los Angeles, California, 90033, United States
University of Vermont
COMPLETED

Burlington, Vermont, 05401, United States
Vseobecna Fakultní Nemocnice
RECRUITING

Prague, 12808, Czechia
Washington University School Of Medicine
COMPLETED

St Louis, Missouri, 63110, United States
Wesley Neurology
COMPLETED

Cordova, Tennessee, 38018, United States
West China Hospital of Sichuan University
COMPLETED

Chengdu, 610041, China
Xiangya Hospital Central South University
RECRUITING

Changsha, 410008, China
Xuanwu Hospital ,Capital Medical University
COMPLETED

Beijing, 100053, China
Yale New Haven Hospital
RECRUITING

New Haven, Connecticut, 06519, United States
iBiomed Research Unit
COMPLETED

Aguascalientes, 20010, Mexico

Conditions

Explore the condition pages connected to this study.

MYASTHENIA GRAVIS