New hope for lupus sufferers: phase 3 trial of nipocalimab begins

NCT ID NCT07438496

Recruiting now Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

First seen Feb 28, 2026 · Last updated May 23, 2026 · Updated 6 times

Summary

This study tests whether nipocalimab can reduce lupus disease activity better than a placebo. It involves 600 adults with moderate to severe lupus. The main goal is to see how many people achieve a meaningful reduction in symptoms after 52 weeks of treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

ARCIS Salud SRL Aprillus asistencia e investigacion
RECRUITING

Buenos Aires, C1406AGA, Argentina
Accurate Clinical Research, Inc.
RECRUITING

Lake Charles, Louisiana, 70605, United States
Advanced Medical Research
RECRUITING

La Palma, California, 90623, United States
Amarillo Center for Clinical Research
RECRUITING

Amarillo, Texas, 79124, United States
Ankara Bilkent Sehir Hastanesi
RECRUITING

Ankara, 06800, Turkey (Türkiye)
Ankara University Medical Faculty
RECRUITING

Ankara, 06050, Turkey (Türkiye)
Arsema
RECRUITING

Ciudad de Buenos Aires, C1427, Argentina
Arthritis & Rheumatic Disease Specialties
RECRUITING

Aventura, Florida, 33180, United States
Arthritis and Rheumatology Research Institute
RECRUITING

Allen, Texas, 75013, United States
Avanti Clinical Research Corp
RECRUITING

Hialeah, Florida, 33013, United States
Carmel Medical Center
RECRUITING

Haifa, 3436212, Israel
Centro Privado de Medicina Familiar
RECRUITING

Buenos Aires, C1417EYG, Argentina
Centro de Investigacion en Enfermedades Reumaticas CIER
RECRUITING

Ciudad de Buenos Aires, C1055, Argentina
Clinical Research Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19114, United States
Clinical Research of West Florida
RECRUITING

Tampa, Florida, 33606, United States
Clinical Research of West Florida 1
RECRUITING

Clearwater, Florida, 33765, United States
Cross Creek Medical Clinic
RECRUITING

Fayetteville, North Carolina, 28304 4422, United States
DJL Clinical Research, PLLC
RECRUITING

Charlotte, North Carolina, 28211, United States
David S Hallegua MD A Professional Corporation
RECRUITING

Beverly Hills, California, 90211, United States
ESHO Empresa De Servicos Hospitalares S A
RECRUITING

São Paulo, 01232 010, Brazil
Firat University Hospital
RECRUITING

Elâzığ, 23200, Turkey (Türkiye)
Floridian Clinical Research LLC
RECRUITING

Miami Lakes, Florida, 33016, United States
Fundacao Faculdade Regional De Medicina S Jose Rio Preto Hospital De Base
RECRUITING

São José do Rio Preto, 15090 000, Brazil
Fundacao do ABC Centro Universitario FMABC
RECRUITING

Santo André, 09060 870, Brazil
Galilee Medical Center
RECRUITING

Nahariya, 2210001, Israel
Hadassah Ein-Qarem Medical Center
RECRUITING

Jerusalem, 9112001, Israel
Haywood Hospital
RECRUITING

Stoke-on-Trent, ST6 7AG, United Kingdom
Hospital De Clinicas De Porto Alegre
RECRUITING

Porto Alegre, 90035-903, Brazil
Hospital Sultan Ismail
RECRUITING

Johor Bahru, 81100, Malaysia
Hospital Taiping
RECRUITING

Taiping, 34000, Malaysia
Hospital Umum Sarawak
RECRUITING

Kuching, 93586, Malaysia
Hospital das Clinicas - UFG
RECRUITING

Goiânia, 74605-020, Brazil
Inland Rheumatology Clinical Trials Inc.
RECRUITING

Upland, California, 91786, United States
Instituto de Investigaciones Clinicas Quilmes
RECRUITING

Quilmes, B1878GEG, Argentina
Joint and Muscle Research Institute
RECRUITING

Charlotte, North Carolina, 28204, United States
Kaohsiung Chang Gung Memorial Hospital
RECRUITING

Kaohsiung City, 83301, Taiwan
Kaohsiung Veterans General Hospital
RECRUITING

Kaohsiung City, 813414, Taiwan
LMK Servicos Medicos S S
RECRUITING

Porto Alegre, 90480 000, Brazil
LeJenue Research Associates PLLC
RECRUITING

Miami, Florida, 33126, United States
Linfen Central Hospital
RECRUITING

Linfen, 041000, China
Linkou Chang Gung Memorial Hospital
RECRUITING

Taoyuan, 333, Taiwan
MR Medicina Reumatologica
RECRUITING

San Fernando, B1646GHP, Argentina
Marmara University Istanbul Pendik Education and Research Hospital
RECRUITING

Istanbul, 34899, Turkey (Türkiye)
Meir Medical Center
RECRUITING

Kfar Saba, 4428164, Israel
NTU Biomedical Park Hospital
RECRUITING

Hsinchu, 302058, Taiwan
Necmettin Erbakan University Meram Medical Faculty
RECRUITING

Konya, 42080, Turkey (Türkiye)
Ningbo medical center lihuili hospital
RECRUITING

Ningbo, 315041, China
Paramount Medical Research & Consulting
RECRUITING

Middleburg Heights, Ohio, 44130, United States
Peking University People's Hospital
RECRUITING

Beijing, 100044, China
Peterborough City Hospital
RECRUITING

Peterborough, PE3 9GZ, United Kingdom
R and H Clinical Research
RECRUITING

Katy, Texas, 77449, United States
Rambam Health Care Campus
RECRUITING

Haifa, 3109601, Israel
Sanko Universitesi Hastanesi
RECRUITING

Gaziantep, 27090, Turkey (Türkiye)
Shanxi Bethune Hospital
RECRUITING

Taiyuan, 030032, China
Shenshan Medical Center Memorial Hospital of Sun Yat Sen University
RECRUITING

Shanwei, 516601, China
Shinkenko Clinic
RECRUITING

Naha, 900 0015, Japan
Solace Clinical Research California
RECRUITING

Tustin, California, 92780, United States
Southampton University Hospital
RECRUITING

Southampton, SO16 6HU, United Kingdom
Southland Arthritis and Osteoporosis Medical Center Inc dba Southland Arthritis
RECRUITING

Hemet, California, 92543, United States
Southwest Rheumatology Research LLC
RECRUITING

Mesquite, Texas, 75150, United States
St. Luke's International Hospital
RECRUITING

Tokyo, 104 8560, Japan
Sunway Medical Centre
RECRUITING

Petaling Jaya, 47500, Malaysia
Taipei Veterans General Hospital
RECRUITING

Taipei, 11217, Taiwan
Tel Aviv Sourasky Medical Center
RECRUITING

Tel Aviv, 6423906, Israel
Texas Rheumatology Research Institute LLC
RECRUITING

Plano, Texas, 75024, United States
Tokai University Hospital
RECRUITING

Isehara, 259-1193, Japan
University Malaya Medical Centre
RECRUITING

Kuala Lumpur, 59100, Malaysia
West Tennessee Research Institute
RECRUITING

Jackson, Tennessee, 38305, United States
Willow Rheumatology and Wellness PLLC
RECRUITING

Willowbrook, Illinois, 60527, United States

Conditions

Explore the condition pages connected to this study.

LUPUS ERYTHEMATOSUS, SYSTEMIC