New hope for controlling debilitating nosebleeds in rare disease

NCT ID NCT04976036

Summary

This study is testing whether a drug called nintedanib can reduce the frequency and severity of nosebleeds in people with hereditary hemorrhagic telangiectasia (HHT), a rare genetic disorder. About 48 adult participants with moderate to severe nosebleeds will be randomly assigned to take either nintedanib capsules or a placebo (inactive pill) twice daily for 16 weeks. The main goal is to see if the drug significantly reduces the total time spent bleeding from the nose compared to the placebo.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Angiology Department, Lausanne University Hospital

    COMPLETED

    Lausanne, Canton of Vaud, 1011, Switzerland

  • Clermont-Ferrand university hospital

    RECRUITING

    Clermont-Ferrand, 63000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lyon University Hospital, Dpt of genetics

    RECRUITING

    Bron, 69677, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.