Can smarter tools make root canal retreatments less painful?
NCT ID NCT07783945
First seen Aug 25, 2026 · Last updated Aug 26, 2026 · Updated 1 time
Summary
This trial tests four different nickel-titanium tool combinations used during a single-visit root canal retreatment. The goal is to see which approach leads to less pain after the procedure and a shorter time in the dentist's chair. Adults with previously treated but inadequately filled lower molars are randomly assigned to one of the four tool groups. Pain levels, painkiller use, and total procedure time are then compared.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Different nickel-titanium rotary and reciprocating instruments used for root canal retreatment and shaping
- What this could lead to
- If one tool combination works better, it could make root canal retreatments faster and less painful for patients.
- What could go wrong
- This is a small, early-stage trial, and results may not apply to all teeth or patients. Pain is subjective and can vary widely.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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109 people
The number who actually took part.
- Started
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Mar 2023
- Finished
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Mar 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients between 18- 65 years of ages * Patients who agree to participate this study * Patients had not used analgesic or antibiotics in last 7 days * Mandibular molar teeth that have been endodontically treated only once * Asymptomatic teeth with previous endodontic treatment but exhibiting inadequate root canal filling on radiographic examination. * Teeth, although asymptomatic, but with newly developed periapical radiolucency within two years compared to the radiographic findings present 2 years ago at the time of root canal treatment was done. * Teeth with periapical radiolucency, but with increased or unchanged according to pre-treatment radiography. * Absence of a history of allergy to local anesthetics, medications, resin-based restorative materials or nickel. Exclusion Criteria: * Pregnant patients and patients in lactation period * Having used corticosteroids in the last 6 months. * Individuals with systemic diseases (endocarditis, immune system diseases, etc.) requiring antibiotic prophylaxis * Having received immunosuppressive therapy within the last week * Gingival recession exceeding 3 mm, deep periodontal pocketing, tooth mobility, or progressive periodontal disease * The presence of a foreign body in the root canal that prevents entry (broken file, post, etc.) * Fracture or crack in the root * Teeth that cannot reach the working length due to calcification in the root canal and step formation * Teeth that cannot be restored due to excessive loss of material in the coronal structure * The presence of more than one adjacent tooth requiring endodontic treatment that may cause reflected pain in the same patient. * Teeth that develop any complications (breakage of endodontic file, perforation, inability to determine the working length with the apex finder) during the removal of the canal filling material.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Aydın Adnan Menderes University, Faculty of Dentistiry
Aydin, Ege, 09000, Turkey (Türkiye)
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