One-Time gene infusion aims to tame PKU for years

NCT ID NCT06061614

First seen Mar 02, 2026 · Last updated May 16, 2026 · Updated 9 times

Summary

This early-phase trial tests a single intravenous dose of NGGT002, a gene therapy for adults with phenylketonuria (PKU). PKU is a genetic condition that causes harmful buildup of phenylalanine (Phe) in the blood, requiring a strict low-protein diet. The study will enroll 15 participants and follow them for 5 years to check safety and whether the treatment can lower blood Phe levels enough to allow a more normal diet.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital of Bengbu Medical College

    RECRUITING

    Bengbu, Anhui, 233000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.