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Powder could replace needles and clips for stomach bleeds

NCT ID NCT06188585

Recruiting now Disease control Sponsor: Medtronic - MITG Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a new hemostatic powder, Nexpowder™, to standard treatments (like clips, heat, or injections) for stopping high-risk bleeding in the upper digestive tract. About 278 adults with active bleeding from ulcers, tumors, or tears will be randomly assigned to one of the two approaches. The main goal is to see if the powder works as well as standard therapy in preventing further bleeding within 7 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Nexpowder™ (hemostatic powder)
What this could lead to: If successful, this could offer a simpler, equally effective first-line treatment for serious upper gastrointestinal bleeding, potentially reducing the need for more complex procedures.
What could go wrong: This is a non-inferiority trial, meaning it only aims to show the powder is not worse than standard care, not that it is better. The study is still recruiting, and results may not apply to all bleeding types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Gastrointestinal Hemorrhage peptic ulcer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE GASTROINTESTINAL BLEEDING

Contacts and locations

Locations

Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States
Cleveland Clinic London
RECRUITING

London, United Kingdom
Copenhagen University Hospital
RECRUITING

Hvidovre, Denmark
Emek Medical Center
RECRUITING

Afula, Israel
McGill University
RECRUITING

Montreal, Quebec, Canada
NYU Langone
RECRUITING

New York, New York, 10016, United States
Northwell Health
RECRUITING

Manhasset, New York, 11030, United States
Odense University Hospital
RECRUITING

Odense, Denmark
RUSH University
RECRUITING

Chicago, Illinois, 60612, United States
Rutgers University
RECRUITING

Piscataway, New Jersey, 08901, United States
St. Antoine
RECRUITING

Paris, France
St. Michael's Hospital
RECRUITING

Toronto, Canada
Vancouver General Hospital
RECRUITING

Vancouver, Canada
Yale
RECRUITING

New Haven, Connecticut, 06520, United States