French study explores genome screening for newborns

NCT ID NCT06875089

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study aims to see if it is feasible and acceptable to use genome sequencing to screen newborns for rare diseases in France. Researchers will offer the test to parents of 2,500 newborns across five hospitals, targeting treatable and actionable genetic conditions. The study will also explore why some parents decline and the emotional impact on families who receive results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could pave the way for routine genome-based newborn screening in France, enabling early detection and management of rare diseases.
What could go wrong
This is a small pilot study (2,500 newborns) focused on feasibility, not on proving health benefits. It may not show clear clinical utility or be accepted by all families.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Besançon

    NOT_YET_RECRUITING

    Besançon, 25000, France

  • CHU Dijon Bourgogne

    RECRUITING

    Dijon, 21000, France

  • CHU Hôtel Dieu

    NOT_YET_RECRUITING

    Nantes, 44093, France

  • CHU Rennes - Hôpital Sud

    NOT_YET_RECRUITING

    Rennes, 35203, France

  • CHU d'Angers

    NOT_YET_RECRUITING

    Angers, 49933, France