Trial aims to control rare blood cancer without chemotherapy

NCT ID NCT03620903

Summary

This study is testing a new combination of three drugs (bortezomib, rituximab, and ibrutinib) for people newly diagnosed with Waldenström's macroglobulinemia, a rare blood cancer. The goal is to see if this 'chemotherapy-free' approach can effectively control the disease while potentially causing fewer severe side effects than traditional treatments. The trial will enroll about 53 adult patients who have not yet received any treatment for their condition.

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Contacts and locations

Locations

  • 'Alexandra' General Hospital of Athens

    Athens, 11528, Greece

  • DIAKO Ev. Diakonie-Krankenhaus gGmbH, Med. Klinik II

    Bremen, 28239, Germany

  • Gemeinschaftspraxis Dres. Rudolf Schlag, Björn Schöttker, Joachim Haas

    Würzburg, 97080, Germany

  • Hämato-Onkologische Gemeinschaftspraxis Pasing-Fürstenfeldbruck

    München, 81241, Germany

  • Kliniken Maria Hilf GmbH (Krankenhaus St. Franziskus), Medizinische Klinik I (Klinik f. Hämatologie, Onkologie, Gastroentereologie)

    Mönchengladbach, 41063, Germany

  • Kliniken Ostalb Stauferklinikum Schwäbisch Gmünd, Zentrum für Innere Medizin

    Mutlangen, 73557, Germany

  • Klinikum der Universität München, Medizinische Klinik und Poliklinik III

    München, 83177, Germany

  • Studiengesellschaft Onkologie Bielefeld GbR

    Bielefeld, 33604, Germany

  • Universitätsklinikum Halle, Klinik für Innere Medizin IV

    Halle, 06120, Germany

  • Universitätsklinikum Münster, Med. Klinik A

    Münster, 48149, Germany

  • Universitätsklinikum Ulm; Klinik für Innere Medizin Innere Medizin III

    Ulm, 89081, Germany

  • Universtätsmedizin Mannheim, III. Medizinische Klinik Studienzentrale im MCC

    Mannheim, 68167, Germany

Conditions

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