New combo therapy aims to slow advanced rectal cancer in first-line trial

NCT ID NCT07383285

First seen Feb 03, 2026 · Last updated May 17, 2026 · Updated 10 times

Summary

This study tests whether adding radiation and two immunotherapy drugs to standard chemotherapy can help people with a specific type of advanced rectal cancer (RAS-mutant, MSS) live longer without the disease getting worse. About 106 adults aged 18-75 will be randomly assigned to receive either the standard treatment or the enhanced combination. The main goal is to see how many patients are still progression-free after 12 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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