New vaccine aims to shield infants from 25 strains of pneumonia

NCT ID NCT06790290

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This Phase 2 trial is testing a new vaccine called IVT PCV-25 in healthy infants to see if it is safe and triggers a strong immune response. The vaccine targets 25 types of pneumococcal bacteria, which can cause serious illnesses like pneumonia and meningitis. Around 421 babies will receive either the new vaccine or an existing one, with doses given at 6, 10, and 14 weeks of age. Researchers will monitor for side effects and measure antibody levels to compare the vaccines.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

25-valent pneumococcal conjugate vaccine (IVT PCV-25)

What this could lead to

If successful, this vaccine could protect infants against 25 types of pneumococcal bacteria, potentially preventing more cases of pneumonia, meningitis, and bloodstream infections than current vaccines.

What could go wrong

This is a Phase 2 trial, so it's still early. The vaccine may not work as well as hoped, or could cause unexpected side effects. Results from 421 infants may not apply to all populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pneumococcal infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Grand Centennial Homes Clinic

    Kawit, Cavite, Philippines

  • Health Index Multispecialty Clinic

    Bacoor, Cavite, Philippines

  • University of the Philippines-National Health Institute_Doña Nena Health Center

    Pasay, National Capital Region, Philippines