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One pill vs. a shot: race for a simpler gonorrhea cure

NCT ID NCT03959527

Completed Disease control Sponsor: Global Antibiotics Research and Development Partnership Source: ClinicalTrials.gov ↗

Summary

This large, completed Phase 3 trial tested whether a single oral dose of a new antibiotic, zoliflodacin, works as well as the current standard treatment (a shot plus a pill) for uncomplicated gonorrhea. Over 1,000 participants with gonorrhea were randomly assigned to receive either the new single pill or the standard combination treatment. The main goal was to see if the new pill could clear the bacterial infection as effectively as the current therapy.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Bangrak STI Center

    Bangkok, 10120, Thailand

  • Bell Flower Clinic

    Indianapolis, Indiana, 46202, United States

  • Institute of HIV Research and Innovation

    Bangkok, 10330, Thailand

  • Institute of Tropical Medicine

    Antwerp, 2000, Belgium

  • Jefferson County Department of Health

    Birmingham, Alabama, 35233, United States

  • Louisiana State University Health Sciences Center

    New Orleans, Louisiana, 70112, United States

  • Masiphumelele Research Site

    Cape Town, 7975, South Africa

  • Ndlovu Research Centre

    Elandsdoorn, 0470, South Africa

  • Public Health - Seattle & King County STD Clinic

    Seattle, Washington, 98104, United States

  • Public Health Service (GGD) Amsterdam / STI Outpatient Clinic

    Amsterdam, 1018 WT, Netherlands

  • SAMRC Botha's Hill Clinical Research Site

    Bothas Hill, 3660, South Africa

  • SAMRC Tongaat Clinical Research Site

    Tongaat, 4400, South Africa

  • San Francisco Department Of Public Health City Clinic

    San Francisco, California, 94103, United States

  • Setshaba Research Centre

    Soshanguve, 0152, South Africa

  • Silom Community Clinic

    Bangkok, 10400, Thailand

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294-0006, United States

  • Wits RHI

    Johannesburg, 2001, South Africa

Conditions

Explore the condition pages connected to this study.

GONORRHEA