New drug challenges standard therapy for debilitating nerve disease

NCT ID NCT06742190

Recruiting now Disease control Sponsor: argenx Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a new drug called empasiprubart works as well as or better than the current standard treatment (IVIg) for adults with multifocal motor neuropathy (MMN), a rare condition that causes muscle weakness. About 115 participants will be randomly assigned to receive either the new drug or IVIg for the first part of the study, with the option to continue on the new drug later. The main goal is to see if the new drug improves grip strength in the most affected hand after 24 weeks.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AHEPA University General Hospital of Thessaloniki
ACTIVE_NOT_RECRUITING

Thessaloniki, 546 36, Greece
AP-HM- Hôpital de La Timone
ACTIVE_NOT_RECRUITING

Marseille, 13005, France
AP-HM- Hôpital de La Timone
ACTIVE_NOT_RECRUITING

Marseille, 13385, France
AP-HP - Hôpital Bicêtre
ACTIVE_NOT_RECRUITING

Le Kremlin-Bicêtre, 94270, France
AP-HP - Hôpital de la Pitié Salpétrière
ACTIVE_NOT_RECRUITING

Paris, 75013, France
Aarhus Universitetshospital
ACTIVE_NOT_RECRUITING

Aarhus, 8200, Denmark
Alexianer - MVZ St. Josefs-Krankenhaus Potsdam GmbH
ACTIVE_NOT_RECRUITING

Potsdam, 14471, Germany
Amsterdam UMC
ACTIVE_NOT_RECRUITING

Amsterdam, 1105 AZ, Netherlands
Az. Ospedaliera Universitaria Policlinico G. Martino
ACTIVE_NOT_RECRUITING

Messina, 98124, Italy
Azienda Ospedaliera Universitaria Careggi
ACTIVE_NOT_RECRUITING

Florence, 50134, Italy
Azienda Ospedaliero-Universitaria San Luigi Gonzaga
ACTIVE_NOT_RECRUITING

Milan, 20133, Italy
Azienda Ospedaliero-Universitaria Sant'Andrea
ACTIVE_NOT_RECRUITING

Roma, 00189, Italy
Brain and Mind Center
ACTIVE_NOT_RECRUITING

Sydney, 2609, Australia
CHU Limoges - Dupuytren 1
ACTIVE_NOT_RECRUITING

Limoges, 87042, France
CHU de Bordeaux - Hôpital Pellegrin
ACTIVE_NOT_RECRUITING

Bordeaux, 33000, France
CHU de Brest - Hôpital La Cavale Blanche
ACTIVE_NOT_RECRUITING

Brest, 29609, France
CHU de Nice-Hôpital Pasteur
ACTIVE_NOT_RECRUITING

Nice, 6001, France
CHU de Strasbourg - Hôpital de Hautepierre
ACTIVE_NOT_RECRUITING

Strasbourg, 67200, France
Centrum Medyczne Neurologia Slaska
ACTIVE_NOT_RECRUITING

Katowice, 40-689, Poland
Chiba University Hospital
ACTIVE_NOT_RECRUITING

Chūōku, 260-8677, Japan
Columbia University Medical Center
ACTIVE_NOT_RECRUITING

New York, New York, 10032, United States
Dent Neurologic Institute Amherst
ACTIVE_NOT_RECRUITING

Amherst, New York, 14226, United States
EZR Research LLC
ACTIVE_NOT_RECRUITING

Boca Raton, Florida, 33486, United States
Escola Bahiana de Medicina e Saude Publica
ACTIVE_NOT_RECRUITING

Salvador, 40290-000, Brazil
Fakultni nemocnice Brno
ACTIVE_NOT_RECRUITING

Brno, 625 00, Czechia
Fakultni nemocnice Hradec Kralove
ACTIVE_NOT_RECRUITING

Hradec Králové, 500 05, Czechia
Fondazione PTV Policlinico Tor Vergata
ACTIVE_NOT_RECRUITING

Roma, 133, Italy
Fondazione Serena Onlus - Centro Clinico NeMO Brescia
ACTIVE_NOT_RECRUITING

Gussago, 25064, Italy
Galen Clinic -- Lublin
ACTIVE_NOT_RECRUITING

Lublin, 20--64, Poland
Gold Coast University Hospital
ACTIVE_NOT_RECRUITING

Southport, 4215, Australia
Healthcare Innovations Institute, LLC
ACTIVE_NOT_RECRUITING

Coral Springs, Florida, 33067, United States
HonorHealth Neurology - Bob Bove Neuroscience Institute - Neurology
ACTIVE_NOT_RECRUITING

Scottsdale, Arizona, 85251, United States
Hospices Civils de Lyon - Hôpital Pierre Wertheimer
ACTIVE_NOT_RECRUITING

Bron, 69500, France
Hospital Clinico San Carlos
ACTIVE_NOT_RECRUITING

Madrid, 28039, Spain
Hospital Das Clinicas da Faculdade de Medicina de Ribeirão Preto
ACTIVE_NOT_RECRUITING

Ribeirão Preto, 14051, Brazil
Hospital General Universitario Dr. Balmis
ACTIVE_NOT_RECRUITING

Alicante, 03010, Spain
Hospital Quironsalud Malaga
ACTIVE_NOT_RECRUITING

Málaga, 29004, Spain
Hospital Universitario Germans Trias i Pujol
ACTIVE_NOT_RECRUITING

Badalona, 08916, Spain
Hospital Universitario Vall d'Hebron
ACTIVE_NOT_RECRUITING

Barcelona, 08035, Spain
Hospital Universitario de Basurto
ACTIVE_NOT_RECRUITING

Madrid, 48013, Spain
Hospital Universitario de Bellvitge
ACTIVE_NOT_RECRUITING

Barcelona, 08907, Spain
Hospital Universitario de Donostia
ACTIVE_NOT_RECRUITING

San Sebastián, 8035, Spain
Hospital de La Santa Creu i Sant Pau
ACTIVE_NOT_RECRUITING

Barcelona, 08041, Spain
Hospital of Lithuanian University of Health Sciences Kauno klinikos
ACTIVE_NOT_RECRUITING

Kaunas, 50161, Lithuania
Huashan Hospital Fudan University
ACTIVE_NOT_RECRUITING

Shanghai, 200040, China
Hôpital Roger Salengro
ACTIVE_NOT_RECRUITING

Lille, 59000, France
Hôpital de la Citadelle
ACTIVE_NOT_RECRUITING

Liège, 4000, Belgium
IRCCS Istituto Clinico Humanitas
ACTIVE_NOT_RECRUITING

Rozzano, 20089, Italy
Indiana University Health Neuroscience Center
ACTIVE_NOT_RECRUITING

Indianapolis, Indiana, 46202, United States
Inselspital - Universitätsspital Bern
ACTIVE_NOT_RECRUITING

Bern, 3010, Switzerland
Institute of Science Tokyo Hospital
ACTIVE_NOT_RECRUITING

Bunkyō City, 113-8519, Japan
John Radcliffe Hospital
ACTIVE_NOT_RECRUITING

Oxford, OX3 7LE, United Kingdom
Juntendo University Hospital
ACTIVE_NOT_RECRUITING

Bunkyō City, 113-8431, Japan
London Health Sciences Centre
ACTIVE_NOT_RECRUITING

London, N6A 5A5, Canada
MICS Centrum Medyczne Bydgoszcz
ACTIVE_NOT_RECRUITING

Bydgoszcz, 85-065, Poland
Medstar Health Research Institute
ACTIVE_NOT_RECRUITING

Washington D.C., District of Columbia, 20010, United States
Musgrove Park Hospital
ACTIVE_NOT_RECRUITING

Taunton, TA1 5DA, United Kingdom
Nagoya University Hospital
ACTIVE_NOT_RECRUITING

Nagoya, 4668560, Japan
National Center of Neurology and Psychiatry
ACTIVE_NOT_RECRUITING

Kodaira, 187-8502, Japan
National Neuromuscular Research Institute
ACTIVE_NOT_RECRUITING

Austin, Texas, 78759-8402, United States
Neuro-Outaouais Clinic
ACTIVE_NOT_RECRUITING

Gatineau, J8Y 1W2, Canada
NeuroCarePlus
ACTIVE_NOT_RECRUITING

Houston, Texas, 77094, United States
Northwestern University
ACTIVE_NOT_RECRUITING

Chicago, Illinois, 60611, United States
Oregon Health and Science University
ACTIVE_NOT_RECRUITING

Portland, Oregon, 97239, United States
Oslo Universitetssykehus HF, Ullevål
ACTIVE_NOT_RECRUITING

Oslo, 0450, Norway
Ospedale Policlinico San Martino IRCCS
ACTIVE_NOT_RECRUITING

Genova, 16132, Italy
Ospedale San Raffaele S.r.l.
ACTIVE_NOT_RECRUITING

Milan, 20132, Italy
PSEG Centro de Pesquisa Clínica
ACTIVE_NOT_RECRUITING

São Paulo, 04038-002, Brazil
Pauls Stradins Clinical University Hospital
ACTIVE_NOT_RECRUITING

Riga, LV-1002, Latvia
Perelman Center for Advanced Medicine
ACTIVE_NOT_RECRUITING

Columbia, Maryland, 21044, United States
Princess Alexandra Hospital
ACTIVE_NOT_RECRUITING

Woolloongabba, 4102, Australia
Queen Elizabeth University Hospital
ACTIVE_NOT_RECRUITING

Glasgow, G51 4TF, United Kingdom
Rigshospitalet-Inge Lehmanns Vej 8
ACTIVE_NOT_RECRUITING

Copenhagen, 2100, Denmark
Royal Hallamshire Hospital
ACTIVE_NOT_RECRUITING

Sheffield, S10 2JF, United Kingdom
Royal Melbourne Hospital
ACTIVE_NOT_RECRUITING

Parkville, 3050, Australia
SP ZOZ Szpital Uniwersytecki w Krakowie
ACTIVE_NOT_RECRUITING

Krakow, 30-688, Poland
Salford Royal Hospital
ACTIVE_NOT_RECRUITING

Salford, M6 8HD, United Kingdom
Samir Macwan, M.D., Inc.
ACTIVE_NOT_RECRUITING

Rancho Mirage, California, 92270, United States
Sociedade de Ensino Superior Estacio de Sa Ltda
ACTIVE_NOT_RECRUITING

Rio de Janeiro, 22620-172, Brazil
St. Paul's Neurology Associates
ACTIVE_NOT_RECRUITING

Vancouver, V6Z 2H2, Canada
Teikyo University Hospital
RECRUITING

tabashi City, 173-8606, Japan

Contact Phone: •••-•••-•••• Email: •••••@•••••
The Cleveland Clinic Foundation
ACTIVE_NOT_RECRUITING

Cleveland, Ohio, 44195, United States
The Neurology Group
ACTIVE_NOT_RECRUITING

Pomona, California, 91767, United States
UC Irvine - MDA ALS and Neuromuscular Center
ACTIVE_NOT_RECRUITING

Columbia, Maryland, 21044, United States
UCK WUM, Centralny Szpital Kliniczny
ACTIVE_NOT_RECRUITING

Warsaw, 02-097, Poland
ULS de Santo António, EPE - Hospital de Santo António
ACTIVE_NOT_RECRUITING

Porto, 4099-001, Portugal
UZ Antwerpen
ACTIVE_NOT_RECRUITING

Edegem, 2650, Belgium
UZ Leuven
ACTIVE_NOT_RECRUITING

Leuven, 3000, Belgium
University Clinical Center of Serbia
ACTIVE_NOT_RECRUITING

Belgrade, 11000, Serbia
University General Hospital ''ATTIKON'' - General Hospital of West Attica H AGIA VARVARA
ACTIVE_NOT_RECRUITING

Chaïdári, 124 62, Greece
University Medical Centre Ljubljana
ACTIVE_NOT_RECRUITING

Ljubljana, 1000, Slovenia
University of California San Francisco
ACTIVE_NOT_RECRUITING

San Francisco, California, 94143, United States
University of Colorado - Anschutz Cancer Pavilion (Neuro Onc Clinic)
ACTIVE_NOT_RECRUITING

Aurora, Colorado, 80045, United States
University of Kansas Medical Center
ACTIVE_NOT_RECRUITING

Fairway, Kansas, 66205, United States
University of Miami Miller School of Medicine
ACTIVE_NOT_RECRUITING

Miami, Florida, 33136, United States
University of Minnesota
ACTIVE_NOT_RECRUITING

Minneapolis, Minnesota, 55414, United States
University of North Carolina at Chapel Hill
ACTIVE_NOT_RECRUITING

Morrisville, North Carolina, 27560, United States
University of South Florida
ACTIVE_NOT_RECRUITING

Tampa, Florida, 33612, United States
Universität Georg August
ACTIVE_NOT_RECRUITING

Göttingen, 37075, Germany
Universitätsklinikum AKH Wien
ACTIVE_NOT_RECRUITING

Vienna, 1090, Austria
Universitätsklinikum Essen
ACTIVE_NOT_RECRUITING

Essen, 45147, Germany
Universitätsklinikum Münster
ACTIVE_NOT_RECRUITING

Münster, 48149, Germany
Universitätsklinikum Schleswig-Holstein - Campus Lübeck
ACTIVE_NOT_RECRUITING

Lübeck, 23538, Germany
Universitätsklinikum Würzburg
ACTIVE_NOT_RECRUITING

Würzburg, 97080, Germany
Univerzitna nemocnica Bratislava
ACTIVE_NOT_RECRUITING

Bratislava, 821 01, Slovakia
Univerzitna nemocnica MARTIN
ACTIVE_NOT_RECRUITING

Martin, 036 59, Slovakia
Vseobecna Fakultni Nemocnice V Praze
ACTIVE_NOT_RECRUITING

Prague, 128 08, Czechia
Yale University School of Medicine
ACTIVE_NOT_RECRUITING

New Haven, Connecticut, 06511, United States
Yamaguchi University Hospital
ACTIVE_NOT_RECRUITING

Ube, 755-0067, Japan

Conditions

Explore the condition pages connected to this study.

MMN MULTIFOCAL MOTOR NEUROPATHY (MMN)