New attack on deadly cancer: powerful drug combo before surgery

NCT ID NCT06155279

Summary

This study is testing whether adding an immunotherapy drug (pembrolizumab) to standard chemotherapy before surgery helps fight pleural mesothelioma more effectively. It involves 41 adults with early-stage, operable mesothelioma who haven't had prior cancer treatment. Patients receive three cycles of the drug combination, then undergo surgery, followed by more immunotherapy to try to control the disease and prevent it from coming back.

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Contacts and locations

Locations

  • Azienda Ospedaliera SS Antonio e Biagio e Cesare Arrigo

    Alessandria, Italy

  • Azienda Ospedaliera-Universitaria di Parma

    Parma, Italy

  • Azienda Ospedaliero-Universitaria S. Anna

    Ferrara, Italy

  • Centro di Riferimento Oncologico (CRO) IRCCS

    Aviano, Pordenone, Italy

  • Humanitas Gavazzeni

    Bergamo, Italia/Bergamo, 24125, Italy

  • IFO - Istituto Tumori Regina Elena, Roma

    Roma, Italia/Roma, 00144, Italy

  • Istituto Clinico Humanitas

    Rozzano, Milano, 20089, Italy

  • Istituto Oncologico Veneto IRCCS

    Padua, 35128, Italy

Conditions

Explore the condition pages connected to this study.