Major trial aims to extend remission for aggressive blood cancer

NCT ID NCT02972840

Ongoing Disease control Sponsor: Acerta Pharma BV Source: ClinicalTrials.gov ↗

Summary

This large, late-stage study is testing whether adding a newer targeted drug (acalabrutinib) to a standard two-drug chemotherapy regimen (bendamustine and rituximab) works better for people newly diagnosed with mantle cell lymphoma. It will compare how long patients live without their cancer getting worse between the two treatment groups. The study is for adults 65 and older who have not had any prior cancer treatment for this condition.

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Contacts and locations

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Locations

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Tucson, Arizona, 85719, United States
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Downey, California, 90241, United States
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Santa Monica, California, 90404, United States
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New Haven, Connecticut, 06510, United States
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Washington D.C., District of Columbia, 20007, United States
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Tallahassee, Florida, 32308-5304, United States
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West Palm Beach, Florida, 33401, United States
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Marietta, Georgia, 30060, United States
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Westwood, Kansas, 66205, United States
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Louisville, Kentucky, 40207, United States
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Ann Arbor, Michigan, 48109, United States
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Rochester, Minnesota, 55905-0001, United States
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Kansas City, Missouri, 64132, United States
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St Louis, Missouri, 63110, United States
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Hackensack, New Jersey, 07601, United States
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Morristown, New Jersey, 07960, United States
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Hawthorne, New York, 10532, United States
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Lake Success, New York, 11042, United States
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Portland, Oregon, 97239, United States
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Charleston, South Carolina, 29425, United States
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Greenville, South Carolina, 29615, United States
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Chattanooga, Tennessee, 37404, United States
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Nashville, Tennessee, 37203, United States
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Houston, Texas, 77030, United States
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San Antonio, Texas, 78217, United States
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Tyler, Texas, 75702, United States
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Charlottesville, Virginia, 22908, United States
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Fort Belvoir, Virginia, 22060, United States
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Seattle, Washington, 98108, United States
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Seattle, Washington, 98109, United States
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Seattle, Washington, 98122, United States
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Morgantown, West Virginia, 26506, United States
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Buenos Aires, C1114AAP, Argentina
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Buenos Aires, C1426ANZ, Argentina
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Buenos Aires, C1430EGF, Argentina
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Buenos Aires, C1431FWO, Argentina
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Caba, C1118AAT, Argentina
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Córdoba, 5000, Argentina
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Bedford Park, 5042, Australia
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Concord, 2139, Australia
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Frankston, 3199, Australia
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Gosford, 2250, Australia
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Heidelberg, 3084, Australia
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Herston, QLD, 4029, Australia
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Kogarah, NSW 2217, Australia
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Murdoch, 6150, Australia
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Nedlands, 6009, Australia
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Newcastle, 2298, Australia
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Southport, 4215, Australia
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Sydney, NSW 2145, Australia
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Woolloongabba, 4102, Australia
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Antwerp, 2060, Belgium
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Ghent, 9000, Belgium
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Leuven, 3000, Belgium
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Roeselare, 8900, Belgium
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Sint-Niklaas, 9100, Belgium
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Bela Vista, 01321-001, Brazil
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Curitiba, 81520-060, Brazil
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Porto Alegre, 90035-903, Brazil
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Porto Alegre, RS 90610-000, Brazil
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Rio de Janeiro, 20231-050, Brazil
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Salvador, 41253-190, Brazil
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São Paulo, 01232-010, Brazil
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São Paulo, 05652-9000, Brazil
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São Paulo, 1236030, Brazil
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São Paulo, 5403, Brazil
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So Paulo, 08270-070, Brazil
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Vancouver, British Columbia, V5Z 4E6, Canada
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Oshawa, Ontario, L1G 2B9,, Canada
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Toronto, Ontario, M4N 3M5, Canada
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Edmonton, T6G 1Z2, Canada
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Greenfield Park, J4V 2H1, Canada
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Halifax, NS B3H 2Y9, Canada
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Beijing, 100036, China
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Changchun, 130021, China
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Changsha, 410008, China
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Changsha, 410013, China
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Chongqing, 400037, China
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Dalian, 116023, China
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Gongshu District, 310022, China
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Haidian District, 100191, China
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Harbin, 150081, China
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Nanchang, 330006, China
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Nanchang, 330029, China
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Nanjing, 210029, China
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Qingdao, 266100, China
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Shanghai, China
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Shenyang, China
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Suzhou, 215006, China
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Tianjian, 300020, China
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Tianjin, China
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Wenzhou, 325000, China
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Wuhan, 430030, China
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Wuhan, 430079, China
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Wuhou District, 610041, China
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Xicheng District, 100050, China
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Xuhui District, 200032, China
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Xuzhou, 221000, China
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Zhengzhou, 450000, China
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Zhengzhou, 450008, China
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Brno, 625 00, Czechia
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Hradec Králové, 500 05, CZ, Czechia
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Ostrava Poruba, 708 52, Czechia
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Pilsen, 30460, CZ, Czechia
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Prague, 100 34, CZ, Czechia
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Argenteuil, 95100, France
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Bobigny, 93000, France
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Bordeaux, 33076, FR, France
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Le Mans, 72000, FR, France
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Limoges, 87042, France
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Pessac, 33604, France
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Périgueux, 24019, France
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Rennes, 35000, France
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Vienne, 86000, FR, France
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Heidelberg, 69120, DE, Germany
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München, 81377, DE, Germany
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Münster, 48149, Germany
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Nordrhein-Westfalen, 52064, DE, Germany
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Ravensburg, 88212, Germany
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Rheinland-Pfalz, 55131, DE, Germany
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Ulm, 89081, Germany
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Athens, 11525, Greece
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Athens, 11527, GR, Greece
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Athens, 11528, GR, Greece
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Ioannina, 45500, GR, Greece
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Pátrai, 26504, Greece
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Thessaloniki, 54007, GR, Greece
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Thessaloniki, 57010, GR, Greece
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Hong Kong, 999077, Hong Kong
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Pok Fu Lam, Hong Kong
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Budapest, 1085, Hungary
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Budapest, 1122, Hungary
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Debrecen, 4032, Hungary
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Győr, 9024, Hungary
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Pécs, 7624, Hungary
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Szeged, 6725, Hungary
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Haifa, 31096, Israel
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Jerusalem, 9103102, Israel
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Petah Tikva, 494142, Israel
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Tel Aviv, 64239, Israel
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Bologna, 40138, Italy
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Milan, 20132, Italy
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Milan, 20162, Italy
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Palermo, 90146, Italy
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Parma, Italy
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Pavia, 27100, Italy
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Reggio Emilia, 42123, Italy
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Rozzano, 20089, Italy
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Turin, 10126, Italy
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Fukuoka, 811-1395, Japan
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Fukuoka, 812-8582, Japan
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Kobe, 650-0047, Japan
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Kyoto, 602-8026, Japan
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Matsuyama, 791-0280, Japan
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Nagoya, 460-0001, Japan
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Nagoya, 464-8681, Japan
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Osaka, 565-0871, Japan
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Sapporo, 003-0006, Japan
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Sendai, 980-8574, Japan
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Shimane, 693-8501, Japan
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Tokyo, 104-0045, Japan
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Tokyo, 135-8550, Japan
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Yokohama, 241-8515, Japan
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Mexico City, 2990, Mexico
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México, 14080, Mexico
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Monterrey, Mexico
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Querétaro, 76090, Mexico
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Dunedin, 9016, New Zealand
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Grafton, 1023, New Zealand
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Otahuhu, 1640, New Zealand
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Arequipa, 5154, Peru
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Bellavista, Peru
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Lima, 1, Peru
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Lima, 34, Peru
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Chorzów, 41-500, Poland
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Krakow, 30-510, Poland
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Lodz, 93-510, Poland
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Lublin, 20-090, Poland
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Olsztyn, 10-228, Poland
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Warsaw, 02-106, Poland
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Warsaw, 02-776, Poland
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Warsaw, 04-141, Poland
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Woj. Podkarpackie, 36-200, Poland
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Wroclaw, 50-367, Poland
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Brasov, 50012, Romania
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Bucharest, 070131, Romania
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Cluj-Napoca, 400124, Romania
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Iași, 700483, Romania
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Pyatigorsk, 357532, Russia
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Saint Petersburg, 197022, Russia
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Saint Petersburg, 197341, Russia
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Saint Petersburg, Russia
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Syktyvkar, 167029, Russia
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Tula, 300053, Russia
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Busan, 49201, South Korea
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Gyeonggi-do, 13620, South Korea
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Seoul, 3080, South Korea
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Seoul, 3722, South Korea
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Seoul, 5505, South Korea
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Seoul, 6351, South Korea
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Seoul, 6591, South Korea
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Seoul, 7985, South Korea
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Badalona, 8916, Spain
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Barcelona, 08041, Spain
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Barcelona, 8003, Spain
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Barcelona, 8035, Spain
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Barcelona, 8907, Spain
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Madrid, 28007, Spain
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Madrid, 28040, Spain
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Madrid, 28046, Spain
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Majadahonda, 28222, Spain
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Pamplona, 31008, Spain
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Seville, Spain
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Valencia, 46026, Spain
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Kaohsiung City, 833, Taiwan
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Taichung, 40447, Taiwan
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Taipei, 100, Taiwan
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Taoyuan District, 333, Taiwan
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Cherkasy, 18009, Ukraine
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Chernihiv, 14029, Ukraine
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Dnipropetrovsk, 49102, Ukraine
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Kiev, 3022, Ukraine
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Lviv, 79044, Ukraine
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Zhytomyr, 10002, Ukraine
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Hanoi, 123, Vietnam
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Hanoi, Vietnam
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Ho Chi Minh City, 700000, Vietnam
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Ho Chi Minh City, WARD 7, Vietnam

Conditions

Explore the condition pages connected to this study.

LYMPHOMA, MANTLE-CELL