New hope for lymphoma patients: major trial tests powerful drug combo

NCT ID NCT06742996

Recruiting now Disease control Sponsor: BeOne Medicines Source: ClinicalTrials.gov ↗

Summary

This study aims to see if adding a new drug called sonrotoclax to an existing drug (zanubrutinib) works better than zanubrutinib alone for adults whose mantle cell lymphoma has returned or stopped responding to prior treatments. It will involve about 300 participants and directly compare the safety and effectiveness of the two-drug combination. The main goal is to see if the combination helps control the cancer for a longer time without it getting worse.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Aichi Cancer Center Hospital Clinical Oncology
RECRUITING

Nagoya, Aichi-ken, 464-8681, Japan
Aidport Sp Z O O
RECRUITING

Skorzewo, 60-185, Poland
Antalya Memorial Hospital
RECRUITING

Dokuma, 07025, Turkey (Türkiye)
Asan Medical Center
RECRUITING

SongpaGu, Seoul Teugbyeolsi, 05505, South Korea
Atrium Health Levine Cancer Institute (Lci)
RECRUITING

Charlotte, North Carolina, 28204-2990, United States
Atrium Health Wake Forest Baptist
RECRUITING

Winston-Salem, North Carolina, 27157, United States
Auxilio Mutuo Cancer Center
RECRUITING

San Juan, 00917, Puerto Rico
Azienda Sanitaria Universitaria Giuliano Isontina
RECRUITING

Trieste, 34129, Italy
Beatson West of Scotland Cancer Centre
RECRUITING

Glasgow, G12 0YN, United Kingdom
Beijing Cancer Hospital
RECRUITING

Beijing, Beijing Municipality, 100142, China
Beijing Hospital
RECRUITING

Beijing, Beijing Municipality, 100730, China
Box Hill Hospital
RECRUITING

Box Hill, Victoria, VIC 3128, Australia
Centre Hospitalier Universitaire Nantes Hotel Dieu
RECRUITING

Nantes, 44000, France
Centroricerche Cliniche Di Verona Srl
RECRUITING

Verona, 37134, Italy
Chiba Cancer Center
RECRUITING

Chiba, Chiba, 260-8717, Japan
Christchurch Hospital
RECRUITING

Christchurch, 8011, New Zealand
Chu Hopital Lyon Sud
RECRUITING

PierreBenite, 69495, France
Chu Montpellier Hopital Saint Eloi
RECRUITING

Montpellier, 34090, France
Chu Tours Hopital Bretonneau
RECRUITING

Tours, 37000, France
Clatterbridge Cancer Centre
RECRUITING

Metropolitan Borough of Wirral, CH63 4JY, United Kingdom
Cleveland Clinic Florida
RECRUITING

Weston, Florida, 33331-3609, United States
Cleveland Clinic Foundation
RECRUITING

Cleveland, Ohio, 44195-0001, United States
Concord Repatriation General Hospital
RECRUITING

Concord, New South Wales, NSW 2139, Australia
Dana Farber Cancer Institute Longwood Medical Center
RECRUITING

Boston, Massachusetts, 02215-5418, United States
Dept of Medicine Iii, University Hospitallmu
RECRUITING

München, 81377, Germany
Derriford Hospital
RECRUITING

Plymouth, PL6 8DH, United Kingdom
Dokkyo Medical University Saitama Medical Center
RECRUITING

Koshigaya, Saitama, 503-8502, Japan
Dolnoslaskie Centrum Onkologii, Pulmonologii I Hematologii
RECRUITING

Wroclaw, 53-439, Poland
Duke University
RECRUITING

Durham, North Carolina, 27710, United States
Dunedin Hospital
RECRUITING

Dunedin, 9016, New Zealand
Etlik City Hospital
RECRUITING

Ankara, 06170, Turkey (Türkiye)
FUNDALEU
RECRUITING

Caba, CP1114, Argentina
Fort Wayne Medical Oncology and Hematology
RECRUITING

Fort Wayne, Indiana, 46804, United States
Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, Shanghai Municipality, 200000, China
Fujian Medical University Union Hospital
RECRUITING

Fuzhou, Fujian, 350001, China
Fundacao Pio Xii Hospital de Amor de Barretos
RECRUITING

Barretos, 14.784-400, Brazil
Fundacao Universidade de Caxias Do Sul Instituto de Pesquisas Em Saude
RECRUITING

Petrópolis, 95070-560, Brazil
Genesiscare North Shore
RECRUITING

St Leonards, New South Wales, NSW 2065, Australia
H Puerta de Hierro Majadahonda
RECRUITING

Majadahonda, 28222, Spain
Harbin Medical University Cancer Hospital
RECRUITING

Harbin, Heilongjiang, 150000, China
Hattiesburg Hematology and Oncology Clinic
RECRUITING

Hattiesburg, Mississippi, 39401-7233, United States
Hcfmusp Servico de Hematologia, Hemoterapia E Terapia Celular
RECRUITING

São Paulo, 05402-000, Brazil
Hiroshima Red Cross Hospital and Atomic Bomb Survivors Hospital
RECRUITING

Hiroshima, Hiroshima, 730-8619, Japan
Hokkaido University Hospital
RECRUITING

Sapporo, Hokkaido, 060-8648, Japan
Hospital Aleman
RECRUITING

CABA, 1425, Argentina
Hospital Clinic de Barcelona
RECRUITING

Barcelona, 08036, Spain
Hospital Do Cancer de Pernambuco
RECRUITING

Recife, 50040-000, Brazil
Hospital Erasto Gaertner
RECRUITING

Curitiba, 81520-060, Brazil
Hospital Felicio Rocho
RECRUITING

Belo Horizonte, 30110-068, Brazil
Hospital Italiano de Buenos Aires
RECRUITING

Ciudad Autonoma Buenos Aires, 1413, Argentina
Hospital Santa Rita de Cassia Afecc
RECRUITING

Vitória, 29043-260, Brazil
Hospital Universitario Fundacion Jimenez Diaz
RECRUITING

Madrid, 28040, Spain
Hospital Universitario de Cordoba
RECRUITING

Córdoba, X5000HUA, Argentina
Hospital de Clinicas de Porto Alegre
RECRUITING

Porto AlegreRS, 900350-903, Brazil
Ico H Duran I Reynals
RECRUITING

Barcelona, 08907, Spain
Institute of Science Tokyo Hospital
RECRUITING

Bunkyoku, Tokyo, 113-8519, Japan
Instituto Joinvilense de Hematologia E Oncologia
RECRUITING

Joinville, 89201-260, Brazil
Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori Irst
RECRUITING

Meldola, 47014, Italy
Jiangsu Province Hospital
RECRUITING

Nanjing, Jiangsu, 210029, China
Jiangxi Province Cancer Hospital
RECRUITING

Nanchang, Jiangxi, 330029, China
Kagoshima University Hospital
RECRUITING

Kagoshima, Kagoshima-ken, 890-8520, Japan
Kanagawa Cancer Center
RECRUITING

Yokohama, Kanagawa, 241-8515, Japan
Klinikum Chemnitz Ggmbh
RECRUITING

Chemnitz, 09116, Germany
Klinikum Der Johann Wolfgang Goethe Universitat
RECRUITING

Frankfurt am Main, 60596, Germany
Kobe City Medical Center General Hospital
RECRUITING

KobeShi, Hyōgo, 650-0047, Japan
Kocaeli Universitesi Tip Fakultesi
RECRUITING

Kocaeli, 41380, Turkey (Türkiye)
Kurashiki Central Hospital
RECRUITING

Kurashikishi, Okayama-ken, 710-8602, Japan
Liaoning Cancer Hospital and Institute
RECRUITING

Shenyang, Liaoning, 110042, China
Linear Clinical Research
RECRUITING

Nedlands, Western Australia, WA 6009, Australia
Linyi Cancer Hospital
RECRUITING

Linyi, Shandong, 276001, China
Matsuyama Red Cross Hospital
RECRUITING

Matsuyama, Ehime, 790 8524, Japan
Mayo Clinic Phoenix
RECRUITING

Phoenix, Arizona, 85054-4502, United States
Mayo Clinic Rochester
RECRUITING

Rochester, Minnesota, 55905-0001, United States
McGlinn Cancer Institute
RECRUITING

West Reading, Pennsylvania, 19611-2143, United States
Md Anderson Cancer Center
RECRUITING

Houston, Texas, 77030-3907, United States
Medical University Vienna Oncology
RECRUITING

Vienna, 1090, Austria
Memorial Cancer Institute, Memorial Healthcare System
RECRUITING

Pembroke Pines, Florida, 33026-4119, United States
Mission Cancer and Blood
RECRUITING

Waukee, Iowa, 50263, United States
Monash Health
RECRUITING

Clayton, Victoria, VIC 3168, Australia
Nanfang Hospital of Southern Medical University
RECRUITING

Guangzhou, Guangdong, 510515, China
National Hospital Organization Okayama Medical Center
RECRUITING

Okayama, 701-1192, Japan
Nebraska Cancer Specialists
RECRUITING

Omaha, Nebraska, 68130-2042, United States
Nebraska Cancer Specialists St Francis Grand Island
RECRUITING

Grand Island, Nebraska, 68803, United States
North Shore Hospital
RECRUITING

Auckland, 0622, New Zealand
Northwest Cancer Specialist, Pc(Us Oncology Research)
RECRUITING

Vancouver, Washington, 98684-6930, United States
Ogaki Municipal Hospital
RECRUITING

Ōgaki, Gifu, 503-8502, Japan
Ohio Health Research Institute
RECRUITING

Columbus, Ohio, 43214-3907, United States
Ohio State University Comprehensive Cancer Center
RECRUITING

Columbus, Ohio, 43210-1280, United States
One Clinical Research
RECRUITING

Nedlands, Western Australia, WA 6009, Australia
Ordensklinikum Linz Gmbh Elisabethinen
RECRUITING

Linz, 4020, Austria
Osaka Metropolitan University Hospital
RECRUITING

Osaka, 545-8586, Japan
Osaka Red Cross Hospital
RECRUITING

Osakashi, Osaka, 543-8555, Japan
Ospedale Vito Fazzi, Asl Lecce
RECRUITING

Leece, 73100, Italy
Oxford University Hospitals Nhs Trust Churchill Hospital
RECRUITING

Headington, OX3 7LE, United Kingdom
Penn State Milton S Hershey Medical Center
RECRUITING

Hershey, Pennsylvania, 17033, United States
Perth Blood Institute
RECRUITING

West Perth, Western Australia, WA 6005, Australia
Policlinico Sorsola Malpighi, Aou Di Bologna
RECRUITING

Bologna, 40138, Italy
Pratia McM Krakow
RECRUITING

Krakow, 30-727, Poland
Pusan National University Hospital
RECRUITING

Seogu, Busan Gwang'yeogsi, 49241, South Korea
Rockingham Hospital
RECRUITING

Cooloongup, Western Australia, WA 6168, Australia
Rush University Medical Center
RECRUITING

Chicago, Illinois, 60612, United States
Samsung Medical Center
RECRUITING

GangnamGu, Seoul Teugbyeolsi, 06351, South Korea
Seoul National University Bundang Hospital
RECRUITING

Seongnam-si, Gyeonggi-do, 13620, South Korea
Seoul National University Hospital
RECRUITING

Seoul, Seoul Teugbyeolsi, 03080, South Korea
Severance Hospital Yonsei University Health System
RECRUITING

SeodaemunGu, Seoul Teugbyeolsi, 03722, South Korea
Shaanxi Provincial Peoples Hospital
RECRUITING

Xi'an, Shaanxi, 710068, China
Sichuan Academy of Medical Sciences and Sichuan Provincial Peoples Hospital
RECRUITING

Chengdu, Sichuan, 610071, China
Stauferklinikum Schwabisch Gmund Kliniken Ostalb
RECRUITING

Mutlangen, 73557, Germany
Sun Yat Sen University Cancer Center
RECRUITING

Guangzhou, Guangdong, 510060, China
Sunshine Coast Hospital and Health Service
RECRUITING

Birtinya, Queensland, QLD 4575, Australia
Tauranga Hospital
RECRUITING

Tauranga, 3112, New Zealand
Tennesse Oncology Chattanooga Downtown
RECRUITING

Chattanooga, Tennessee, 37404, United States
Tennessee Oncology
RECRUITING

Nashville, Tennessee, 37205, United States
Texas Oncology Austin Midtown
RECRUITING

Round Rock, Texas, 78681-4019, United States
The Affiliated Hospital of Qingdao University Branch West Coast
RECRUITING

Qingdao, Shandong, 266555, China
The Affiliated Hospital of Xuzhou Medical University
RECRUITING

Xuzhou, Jiangsu, 221000, China
The Cancer and Hematology Centers
RECRUITING

Grand Rapids, Michigan, 49503-2563, United States
The Catholic University of Korea, Seoul St Marys Hospital
RECRUITING

SeochoGu, Seoul Teugbyeolsi, 06591, South Korea
The Catholic University of Korea, Yeouido St Marys Hospital
RECRUITING

Yeongdeungpo-gu, Seoul Teugbyeolsi, 07345, South Korea
The First Affiliated Hospital of Chongqing Medical University
RECRUITING

Chongqing, Chongqing Municipality, 630014, China
The First Affiliated Hospital of Wenzhou Medical University
RECRUITING

Wenzhou, Zhejiang, 325000, China
The First Affiliated Hospital of Zhengzhou University
RECRUITING

Zhengzhou, Henan, 450052, China
The First Affiliated Hospital, Zhejiang University School of Medicinechengzhan
RECRUITING

Hangzhou, Zhejiang, 310002, China
The Royal Bournemouth and Christchurch Hospitals Nhs Foundation
RECRUITING

Bournemouth, BH7 7DW, United Kingdom
The Valley Hospital, Inc
RECRUITING

Paramus, New Jersey, 07652, United States
Tohoku University Hospital
RECRUITING

Sendai, Miyagi, 980-8574, Japan
Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology
RECRUITING

Wuhan, Hubei, 430030, China
Toyohashi Municipal Hospital
RECRUITING

Toyohashishi, Aichi-ken, 441-8570, Japan
Uk St Poelten
RECRUITING

Sankt Pölten, 3100, Austria
Union Hospital of Tongji Medical College, Huazhong University of Science and Technology
RECRUITING

Wuhan, Hubei, 430022, China
Universidade de Campinas Centro de Hematologia E Hemoterapia
RECRUITING

Campinas, 13083-878, Brazil
Universitatsklinik Fur Innere Medizin Iii Universitatsklinikum Der Pmu Landeskrankenhaus Salzburg
RECRUITING

Salzburg, 5020, Austria
Universitatsklinikum Halle
RECRUITING

Halle, 06120, Germany
Universitatsklinikum Hamburg Eppendorf
RECRUITING

Hamburg, 20251, Germany
University College Hospital
RECRUITING

London, NW1 2PG, United Kingdom
University Hospitals
RECRUITING

Cleveland, Ohio, 44106-1716, United States
University of Alabama At Birmingham Hospital
RECRUITING

Birmingham, Alabama, 35294-0004, United States
University of Maryland Greenebaum Comprehensive Cancer Center
RECRUITING

Baltimore, Maryland, 21201-1544, United States
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109-1382, United States
University of Virginia
RECRUITING

Charlottesville, Virginia, 22908-0817, United States
Uniwersytecki Szpital Kliniczny Nr W Lublinie
RECRUITING

Lublin, 20-090, Poland
Vcu Massey Cancer Center
RECRUITING

Richmond, Virginia, 23298-5026, United States
Virgina Cancer Specialists
RECRUITING

Gainesville, Virginia, 20155-3257, United States
Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110-1010, United States
Wellington Regional Hospital (Ccdhb)
RECRUITING

Wellington, 6021, New Zealand
Westmead Hospital
RECRUITING

Westmead, New South Wales, NSW 2145, Australia
Wielospecjalistyczne Centrum Onkologii I Traumatologii Im M Kopernika W Lodzi
RECRUITING

Lodz, 93-513, Poland
Yale University, Yale Cancer Center
RECRUITING

New Haven, Connecticut, 06520-8028, United States
Yokohama Municipal Citizens Hospital
RECRUITING

Yokohama, 221-0855, Japan

Conditions

Explore the condition pages connected to this study.

B-CELL LYMPHOMA MANTLE-CELL LYMPHOMA