New hope for lymphoma patients: experimental combo aims to shrink tumors

NCT ID NCT05551936

Summary

This study is testing whether adding a new drug called tazemetostat to a standard two-drug regimen (bendamustine and rituximab) is safe and effective for adults with high-tumor-burden follicular lymphoma who have not had prior treatment. The main goals are to see if the three-drug combination is safe (Phase 1) and if it leads to a complete metabolic response—meaning no detectable cancer on a PET scan—after a short, six-cycle treatment course (Phase 2).

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Contacts and locations

Locations

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

  • University of Illinois Cancer Center

    Chicago, Illinois, 60612, United States

  • University of Wisconsin Carbone Cancer Center

    Madison, Wisconsin, 53705, United States

Conditions

Explore the condition pages connected to this study.