New hope for aggressive lymphoma: experimental drug added to standard treatment

NCT ID NCT04980222

Summary

This study is testing whether adding an experimental drug called glofitamab to standard chemotherapy (R-CHOP) works better for people with high-risk, untreated diffuse large B-cell lymphoma. Researchers will enroll about 46 patients who have specific high-risk markers in their blood. The main goal is to see if this combination is safe and leads to complete disappearance of cancer after treatment ends.

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Contacts and locations

Locations

  • Aarhus Universitetshospital Skejby

    Aarhus N, 8200, Denmark

  • Baylor University Medical Center

    Dallas, Texas, 75204, United States

  • Centre Henri Becquerel

    Rouen, 76038, France

  • City of Hope Comprehensive Cancer Center

    Duarte, California, 91010, United States

  • Hopital Henri Mondor

    Créteil, 94010, France

  • Hospital Clinic i Provincial de Barcelona

    Barcelona, 08036, Spain

  • Hospital Clinico Universitario de Salamanca

    Salamanca, 37007, Spain

  • Hospital General Universitario Gregorio Marañon

    Madrid, 28007, Spain

  • Hospital Univ. 12 de Octubre; Servicio de Hematologia

    Madrid, 28041, Spain

  • Memorial Sloan Kettering Bergen

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Cancer Center at Westchester

    Harrison, New York, 10604, United States

  • Stanford Cancer Center

    Stanford, California, 94305-5820, United States

  • Universitair Medisch Centrum Groningen

    Groningen, 9713 GZ, Netherlands

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • Uniwersytecki Szpital Kliniczny; Klinika Hematologii, Nowotworów Krwi i Transplantacji Szpiku

    Wroclaw, 50-367, Poland

  • Uniwersyteckie Centrum Kliniczne, Klinika Hematologii i Transplantologii

    Gdansk, 80-211, Poland

  • Washington University; Wash Uni. Sch. Of Med

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.