New cancer drug trial aims to beat standard treatment for aggressive lymphoma

NCT ID NCT06890884

Recruiting now Disease control Sponsor: Merck Sharp & Dohme LLC Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a new drug combination works better than the current standard treatment for a fast-growing blood cancer called GCB DLBCL. Researchers will compare zilovertamab vedotin plus R-CHP against polatuzumab vedotin plus R-CHP in 594 people who haven't had any treatment yet. The main goal is to see if more people have their cancer completely disappear with the new combination.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AZ Delta ( Site 0303)
RECRUITING

Roeselare, West-Vlaanderen, 8800, Belgium

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AZ Sint-Maarten, Campus Leopoldstraat 2 ( Site 0306)
RECRUITING

Mechelen, Antwerpen, 2800, Belgium

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Aichi Cancer Center ( Site 1007)
RECRUITING

Nagoya, Aichi-ken, 464-8681, Japan

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Alliance Cancer Specialists (ACS) ( Site 8010)
RECRUITING

Horsham, Pennsylvania, 19044, United States

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Arcispedale Santa Maria Nuova ( Site 0706)
RECRUITING

Reggio Emilia, 42123, Italy

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Atlantic Health Morristown Medical Center ( Site 0163)
RECRUITING

Morristown, New Jersey, 07960, United States

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Az. Osp. Ospedali Riuniti VILLA SOFIA-CERVELLO ( Site 0702)
RECRUITING

Palermo, 90146, Italy

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Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e Cesare Arrigo ( Site 0703)
RECRUITING

Alessandria, 15121, Italy

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Baptist Health Hardin ( Site 0154)
RECRUITING

Elizabethtown, Kentucky, 42701, United States

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Baptist Health Lexington ( Site 0127)
RECRUITING

Lexington, Kentucky, 40503, United States

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Baptist MD Anderson Cancer Center ( Site 0176)
RECRUITING

Jacksonville, Florida, 32207, United States

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Bass Medical Group ( Site 0123)
RECRUITING

Walnut Creek, California, 94598, United States

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Beacon Cancer Care ( Site 0142)
RECRUITING

Post Falls, Idaho, 83854, United States

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Boca Raton Regional Hospital-Lynn Cancer Institute ( Site 0130)
RECRUITING

Boca Raton, Florida, 33486, United States

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Bozeman Health Deaconess Hospital ( Site 0183)
RECRUITING

Bozeman, Montana, 59715, United States

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Bristol Haematology and Oncology Centre ( Site 0908)
RECRUITING

Bristol, Bristol, City of, BS2 8ED, United Kingdom

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Cancer Care Associates Of York ( Site 0174)
RECRUITING

York, Pennsylvania, 17403, United States

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Christie Hospital NHS Trust ( Site 0901)
RECRUITING

Manchester, M20 4BX, United Kingdom

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Churchill Hospital ( Site 0903)
RECRUITING

Oxford, Oxfordshire, OX3 7LJ, United Kingdom

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Clatterbridge Cancer Centre - Liverpool ( Site 0911)
RECRUITING

Liverpool, L7 8YA, United Kingdom

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Cleveland Clinic - Hillcrest Hospital-Hillcrest Hospital Cancer Center ( Site 0199)
RECRUITING

Mayfield Heights, Ohio, 44124, United States

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Cleveland Clinic Main ( Site 0101)
RECRUITING

Cleveland, Ohio, 44195, United States

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Clinical Research Alliance ( Site 0122)
RECRUITING

Westbury, New York, 11590, United States

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Cliniques Universitaires Saint-Luc ( Site 0302)
RECRUITING

Brussels, Bruxelles-Capitale, Region de, 1200, Belgium

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Colorado West Healthcare System-Grand Valley Oncology ( Site 0165)
RECRUITING

Grand Junction, Colorado, 81505, United States

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Edith Wolfson Medical Center ( Site 0602)
RECRUITING

Holon, 5810001, Israel

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Erie County Medical Center ( Site 0175)
RECRUITING

Buffalo, New York, 14215, United States

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Fairview Hospital-Moll Cancer Center ( Site 0198)
RECRUITING

Cleveland, Ohio, 44111, United States

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Fujita Health University Hospital ( Site 1003)
RECRUITING

Toyoake, Aichi-ken, 470-1192, Japan

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Genesis Cancer and Blood Institute ( Site 0193)
RECRUITING

Hot Springs, Arkansas, 71913, United States

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Georgetown University Medical Center ( Site 0117)
RECRUITING

Washington D.C., District of Columbia, 20007, United States

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Guy s & St Thomas NHS Foundation Trust ( Site 0904)
RECRUITING

London, London, City of, SE1 9RT, United Kingdom

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Haddasah Medical Center ( Site 0601)
RECRUITING

Jerusalem, 9112001, Israel

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Hammersmith Hospital ( Site 0915)
RECRUITING

London, London, City of, W12 0 HS, United Kingdom

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Hokkaido University Hospital ( Site 1004)
RECRUITING

Sapporo, Hokkaido, 060-8648, Japan

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Hopital de Jolimont ( Site 0304)
RECRUITING

Haine-Saint-Paul, Hainaut, 7100, Belgium

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IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori" ( Site 0707)
RECRUITING

Meldola, Forli-Cesena, 47014, Italy

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Illinois Cancer Care ( Site 7005)
RECRUITING

Peoria, Illinois, 61615, United States

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Infirmary Cancer Care ( Site 0157)
RECRUITING

Mobile, Alabama, 36607, United States

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Intermountain Healthcare - St. George ( Site 0203)
RECRUITING

St. George, Utah, 84790, United States

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Intermountain Medical Center ( Site 0182)
RECRUITING

Murray, Utah, 84107, United States

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Istituto Clinico Humanitas ( Site 0704)
RECRUITING

Rozzano, Milano, 20089, Italy

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Istituto Europeo di Oncologia ( Site 0701)
RECRUITING

Milan, 20141, Italy

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Kansai Medical University Hospital ( Site 1006)
RECRUITING

Hirakata, Osaka, 573-1191, Japan

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Laura and Isaac Perlmutter Cancer Center at NYU Langone ( Site 0108)
RECRUITING

New York, New York, 10016, United States

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Lincoln County Hospital ( Site 0906)
RECRUITING

Lincoln, Lincolnshire, LN2 5QY, United Kingdom

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Louisiana State University Health Sciences Shreveport ( Site 0195)
RECRUITING

Shreveport, Louisiana, 71103, United States

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Mater Misercordiae University Hospital ( Site 0501)
RECRUITING

Dublin, D07 R2WY, Ireland

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Medical College of Wisconsin ( Site 0103)
RECRUITING

Milwaukee, Wisconsin, 53226, United States

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Medical Oncology Hematology Consultants (MOHC) ( Site 8007)
RECRUITING

Newark, Delaware, 19713, United States

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Mid Florida Hematology and Oncology Center ( Site 0152)
RECRUITING

Orange City, Florida, 32763, United States

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Minnesota Oncology Hematology (MNO) ( Site 8004)
RECRUITING

Burnsville, Minnesota, 55337, United States

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Mission Blood & Cancer Care ( Site 0114)
RECRUITING

Waukee, Iowa, 50263, United States

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Mount Sinai Cancer Center ( Site 0140)
RECRUITING

Miami Beach, Florida, 33140, United States

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NHO Revive Research Institute, LLC ( Site 0121)
RECRUITING

Lincoln, Nebraska, 68506, United States

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Nagasaki University Hospital ( Site 1008)
RECRUITING

Nagasaki, 852-8501, Japan

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Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 0803)
RECRUITING

Warsaw, Masovian Voivodeship, 02-781, Poland

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National Cancer Center Hospital ( Site 1009)
RECRUITING

Chūō, Tokyo, 104-0045, Japan

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National Hospital Organization Sendai Medical Center ( Site 1005)
RECRUITING

Sendai, Miyagi, 983-8520, Japan

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Nippon Medical School Hospital ( Site 1001)
RECRUITING

Bunkyo, Tokyo, 113-8603, Japan

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Northwest Cancer Specialists (Compass Oncology) ( Site 8000)
RECRUITING

Vancouver, Washington, 98684, United States

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Norton Women's and Children's Hospital-Norton Cancer Institute - St. Matthews ( Site 0185)
RECRUITING

Louisville, Kentucky, 40207, United States

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Novant Health Forsyth Medical Center ( Site 0206)
RECRUITING

Winston-Salem, North Carolina, 27103, United States

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Novant Health Presbyterian Medical Center ( Site 0177)
RECRUITING

Charlotte, North Carolina, 28204, United States

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Ochsner Clinic Foundation ( Site 0189)
RECRUITING

New Orleans, Louisiana, 70121, United States

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Ochsner LSU Health - Monroe Medical Center, Family Medicine Clinic ( Site 0209)
RECRUITING

Monroe, Louisiana, 71202, United States

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Otto-Von-Guericke-Universitaet Magdeburg ( Site 0411)
RECRUITING

Magdeburg, Saxony-Anhalt, 39120, Germany

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Our Lady of the Lake Physician Group-Medical Oncology ( Site 0180)
RECRUITING

Baton Rouge, Louisiana, 70808, United States

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Palo Verde Cancer Specialists ( Site 0105)
RECRUITING

Glendale, Arizona, 85304, United States

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Perlmutter Cancer Center at NYU Langone Hospital - Long Island ( Site 0208)
RECRUITING

Mineola, New York, 11501, United States

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Pratia MCM Krakow ( Site 0804)
RECRUITING

Karkow, Lesser Poland Voivodeship, 30-727, Poland

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Pratia Onkologia Katowice ( Site 0801)
RECRUITING

Katowice, Silesian Voivodeship, 40-519, Poland

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Providence Oncology and Hematology Clinic Westside ( Site 0179)
RECRUITING

Portland, Oregon, 97225, United States

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Providence Portland Medical Center ( Site 0120)
RECRUITING

Portland, Oregon, 97213, United States

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Rabin Medical Center ( Site 0607)
RECRUITING

Petah Tikva, 4941492, Israel

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Rambam Health Care Campus ( Site 0604)
RECRUITING

Haifa, 3109601, Israel

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Rocky Mountain Cancer Centers (RMCC) ( Site 8001)
RECRUITING

Aurora, Colorado, 80012, United States

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Roswell Park Cancer Institute ( Site 0192)
RECRUITING

Buffalo, New York, 14263, United States

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Roy and Patricia Disney Family Cancer Center - Providence Saint Joseph Medical Center ( Site 0135)
RECRUITING

Burbank, California, 91505, United States

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Royal Devon & Exeter Hospital ( Site 0910)
RECRUITING

Exeter, Devon, EX2 5DW, United Kingdom

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SCRI Oncology Partners ( Site 7002)
RECRUITING

Nashville, Tennessee, 37203, United States

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SSM Health Dean Medical Group ( Site 0106)
RECRUITING

Madison, Wisconsin, 53715, United States

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SUNY Upstate Cancer Center ( Site 0178)
RECRUITING

Syracuse, New York, 13210, United States

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Saint Elizabeth Medical Center Edgewood ( Site 0141)
RECRUITING

Edgewood, Kentucky, 41017, United States

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Sheba Medical Center ( Site 0603)
RECRUITING

Ramat Gan, 5265601, Israel

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Shimane University Hospital ( Site 1002)
RECRUITING

Izumo, Shimane, 693-8501, Japan

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Soroka Medical Center ( Site 0606)
RECRUITING

Beersheba, 8410101, Israel

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St Vincent's University Hospital ( Site 0502)
RECRUITING

Dublin, Dublin, D04 T6F4, Ireland

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Stoke Mandeville Hospital ( Site 0917)
RECRUITING

Aylesbury, Buckinghamshire, HP21 8AL, United Kingdom

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Szpital Specjalistyczny im. Jedrzeja Sniadeckiego w Nowym Saczu ( Site 0806)
RECRUITING

Nowy Sącz, Lesser Poland Voivodeship, 33-300, Poland

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Tennessee Cancer Specialists ( Site 7004)
RECRUITING

Knoxville, Tennessee, 37909, United States

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Texas Oncology - Central/South Texas ( Site 8006)
RECRUITING

Austin, Texas, 78705, United States

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Texas Oncology - Northeast Texas ( Site 8002)
RECRUITING

Palestine, Texas, 75801, United States

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Texas Oncology - San Antonio ( Site 8009)
RECRUITING

San Antonio, Texas, 78240, United States

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Texas Oncology - West Texas ( Site 8008)
RECRUITING

Amarillo, Texas, 79124, United States

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The James Cook University Hospital ( Site 0909)
RECRUITING

Middlesbrough, England, TS4 3BW, United Kingdom

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The University of Texas Health Science Center at Tyler dba UT Health East Texas HOPE Cancer Center ( Site 0145)
RECRUITING

Tyler, Texas, 75701, United States

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UZ Leuven ( Site 0301)
RECRUITING

Leuven, Vlaams-Brabant, 3000, Belgium

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Uniklinik Erlangen ( Site 0412)
RECRUITING

Erlangen, Bavaria, 91054, Germany

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Universita degli Studi di Napoli Federico II ( Site 0705)
RECRUITING

Naples, 80131, Italy

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Universitaetsklinikum Wuerzburg ( Site 0401)
RECRUITING

Würzburg, Bavaria, 97080, Germany

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University Hospital Limerick ( Site 0503)
RECRUITING

Limerick, V94 F858, Ireland

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University Hospitals Plymouth NHS Trust ( Site 0905)
RECRUITING

Plymouth, Devon, PL68DH, United Kingdom

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University Hospitals of Cleveland ( Site 0155)
RECRUITING

Cleveland, Ohio, 44106, United States

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University Of Nebraska Medical Center ( Site 0110)
RECRUITING

Omaha, Nebraska, 68198, United States

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University of Chicago Medical Center ( Site 0126)
RECRUITING

Chicago, Illinois, 60637, United States

Contact Phone: •••-•••-••••
University of Cincinnati Medical Center ( Site 0156)
RECRUITING

Cincinnati, Ohio, 45219, United States

Contact Phone: •••-•••-••••
University of Iowa-Holden Comprehensive Cancer Center ( Site 0139)
RECRUITING

Iowa City, Iowa, 52242, United States

Contact Phone: •••-•••-••••
University of North Carolina Medical Center ( Site 0136)
RECRUITING

Chapel Hill, North Carolina, 27514, United States

Contact Phone: •••-•••-••••
Uniwersyteckie Centrum Kliniczne ( Site 0802)
RECRUITING

Gdansk, Pomeranian Voivodeship, 80-214, Poland

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VCU Health Adult Outpatient Pavillion ( Site 0138)
RECRUITING

Richmond, Virginia, 23219, United States

Contact Phone: •••-•••-••••
Valley Health Systems - Ridgewood Campus ( Site 0125)
RECRUITING

Paramus, New Jersey, 07652, United States

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Virginia Cancer Specialists, PC ( Site 8003)
RECRUITING

Manassas, Virginia, 20110, United States

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ZIV Medical Center ( Site 0605)
RECRUITING

Safed, 13100, Israel

Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.

LYMPHOMA, LARGE B-CELL, DIFFUSE