First-in-Human trial tests experimental drug for Tough-to-Treat blood cancers

NCT ID NCT06254495

Summary

This is the first study testing a new experimental drug called PF-08046044/SGN-35C in people with advanced lymphoma that has returned or stopped responding to standard treatments. The trial will enroll 57 adults with specific types of lymphoma to determine the safest dose, understand side effects, and see if the drug shows early signs of helping control their cancer. Researchers will test different dosing schedules and monitor how participants respond to the treatment.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LYMPHOMA, LARGE B-CELL, DIFFUSE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Centro Ricerche Cliniche di Verona s.r.l.

    Verona, 37134, Italy

  • City of Hope (City of Hope National Medical Center, City Of Hope Medical Center)

    Duarte, California, 91010, United States

  • Fred Hutchinson Cancer Research Center | Seattle, WA

    Seattle, Washington, 98109, United States

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • IP Address: City of Hope Investigational Drug Services(IDS)

    Duarte, California, 91010, United States

  • Institut Gustave Roussy

    Villejuif, 94805, France

  • Nebraska Medical Center

    Omaha, Nebraska, 68105, United States

  • Nebraska Medicine - Bellevue Medical Center

    Bellevue, Nebraska, 68123, United States

  • Nebraska Medicine - Village Pointe

    Omaha, Nebraska, 68118, United States

  • Rigshospitalet University Hospital of Copenhagen

    Copenhagen Ø, DK 2100, Denmark

  • Robert Wood Johnson University Hospital

    New Brunswick, New Jersey, 08901, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08901, United States

  • Sylvester Comprehensive Cancer Center - Hollywood

    Hollywood, Florida, 33021, United States

  • Sylvester Comprehensive Cancer Center - Kendall

    Miami, Florida, 33176, United States

  • Sylvester Comprehensive Cancer Center- The Lennar Foundation Medical Center

    Coral Gables, Florida, 33146, United States

  • The Christie NHS Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • The Royal Marsden NHS Foundation Trust (RM)

    Sutton, Surrey, SM2 5PT, United Kingdom

  • The University of Kansas Cancer Center - Indian Creek Campus

    Overland Park, Kansas, 66211, United States

  • The University of Kansas Cancer Center - Lee's Summit

    Lee's Summit, Missouri, 64064, United States

  • The University of Kansas Cancer Center - Overland Park

    Overland Park, Kansas, 66210, United States

  • The University of Kansas Cancer Center, Investigational Drug Services

    Fairway, Kansas, 66205, United States

  • The University of Kansas Hospital

    Kansas City, Kansas, 66160, United States

  • The University of Kansas Hospital Cambridge North Tower A

    Kansas City, Kansas, 66160, United States

  • The University of Kansas Medical Center Medical Office Building

    Kansas City, Kansas, 66160, United States

  • University Of Miami Hospital and Clinics/Sylvester Comprehensive Cancer Center

    Miami, Florida, 33136, United States

  • University Of Miami Hospitals And Clinics

    Miami, Florida, 33136, United States

  • University of California, San Francisco Medical Center

    San Francisco, California, 94143, United States

  • University of Kansas Cancer Center

    Westwood, Kansas, 66205, United States

  • University of Kansas Clinical Research Center

    Fairway, Kansas, 66205, United States

  • University of Miami Hospital and Clinics - Deerfield Beach

    Deerfield Beach, Florida, 33442, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

  • University of Washington

    Seattle, Washington, 98195, United States

Conditions

Explore the condition pages connected to this study.